Literature DB >> 14662535

Vaginal reconstruction following resection of primary locally advanced and recurrent colorectal malignancies.

Dougal N D'Souza1, Miguel Pera, Heidi Nelson, Stephan J Finical, Nho V Tran.   

Abstract

HYPOTHESES: Vertical rectus abdominus myocutaneous flap reconstruction facilitates healing within the radiated pelvis and preserves the possibility of subsequent sexual function in patients with colorectal cancer who require partial or complete resection of the vagina.
DESIGN: A retrospective review of a consecutive series of patients.
SETTING: A tertiary referral center. PATIENTS: All patients undergoing surgical treatment of locally advanced or recurrent colorectal cancer and vertical rectus abdominus myocutaneous flap reconstruction of the vagina. INTERVENTION: Vertical rectus abdominus myocutaneous flap reconstruction. MAIN OUTCOME MEASURES: Operative feasibility, complications, and sexual function.
RESULTS: Twelve patients underwent extended resection for primary locally advanced or recurrent colorectal cancer including total or near total vaginectomy. Median age was 47 years. Tumors included 9 rectal adenocarcinomas, 2 anal squamous cell carcinomas, and 1 recurrent cecal adenocarcinoma. Surgical procedures included 8 abdominoperineal resections with posterior exenteration; resection of pelvic tumor and partial vaginectomy in 2 patients with previous abdominoperineal resection; 1 total exenteration; and 1 total proctocolectomy with posterior exenteration. The average operative time for tumor extirpation, irradiation, and reconstruction was more than 9 hours and all patients required blood transfusions. Despite 2 patients having superficial necrosis and 4 having mild wound infections, no patient required reoperation and all achieved complete healing. Five patients reported resuming sexual intercourse.
CONCLUSIONS: The vertical rectus abdominus myocutaneous flap can be successfully used for vaginal reconstruction following resection of locally advanced colorectal cancer. It provides nonirradiated, vascularized tissue that fills the pelvic dead space, allows for stomal placement, and provides a chance for sexual function.

Entities:  

Mesh:

Year:  2003        PMID: 14662535     DOI: 10.1001/archsurg.138.12.1340

Source DB:  PubMed          Journal:  Arch Surg        ISSN: 0004-0010


  10 in total

1.  A hundred patients with vertical rectus abdominis myocutaneous (VRAM) flap for pelvic reconstruction after total pelvic exenteration.

Authors:  R E Horch; W Hohenberger; A Eweida; U Kneser; K Weber; A Arkudas; S Merkel; J Göhl; J P Beier
Journal:  Int J Colorectal Dis       Date:  2014-04-22       Impact factor: 2.571

2.  [Microsurgical reconstruction of the pelvic floor after pelvic exenteration. Reduced morbidity and improved quality of life by an interdisciplinary concept].

Authors:  N M Stechl; S Baumeister; K Grimm; T W Kraus; H Bockhorn; K E Exner
Journal:  Chirurg       Date:  2011-07       Impact factor: 0.955

3.  Modified supralevator pelvic exenteration for the treatment of locally advanced rectal cancer with vaginal and uterine invasion.

Authors:  André Roncon Dias; Sérgio Carlos Nahas
Journal:  Surg Today       Date:  2012-08-21       Impact factor: 2.549

4.  Restoration of vaginal anatomy after extensive posterior wall resection utilizing human acellular dermal matrix.

Authors:  Amit K Bhavsar; Kevin M Lin-Hurtubise; Charles S Dietrich
Journal:  Gynecol Oncol Rep       Date:  2016-01-27

5.  Interdisciplinary Surgical Approaches in Vaginal and Perineal Reconstruction of Advanced Rectal and Anal Female Cancer Patients.

Authors:  Raymund E Horch; Ingo Ludolph; Aijia Cai; Klaus Weber; Robert Grützmann; Andreas Arkudas
Journal:  Front Oncol       Date:  2020-05-13       Impact factor: 6.244

6.  Outcomes Analysis of Gynecologic Oncologic Reconstruction.

Authors:  Lisa M Block; Emily C Hartmann; Jason King; Saygin Chakmakchy; Timothy King; Michael L Bentz
Journal:  Plast Reconstr Surg Glob Open       Date:  2019-01-15

7.  Simultaneous bladder and vaginal reconstruction using ileum in complicated vesicovaginal fistula.

Authors:  Sujata K Patwardhan; Ajit Sawant; Mohammad Ismail; M Nagabhushana; Radheshyam R Varma
Journal:  Indian J Urol       Date:  2008-07

8.  Intestinal obstruction following harvest of VRAM-flap for reconstruction of a large perineal defect.

Authors:  Sherif Elawa; Olof Hallböök; Pär Myrelid; Johann Zdolsek
Journal:  Case Reports Plast Surg Hand Surg       Date:  2015-12-11

9.  Re-exploration of vertical rectus abdominis myocutaneous flap for vaginal reconstruction: Case report and review of the literature.

Authors:  Joshua D Rouch; Andrew Li; Joshua G Cohen; Kevork K Kazanjian; Jaco H Festekjian
Journal:  JPRAS Open       Date:  2017-11-08

10.  Donor Site Morbidity of Patients Receiving Vertical Rectus Abdominis Myocutaneous Flap for Perineal, Vaginal or Inguinal Reconstruction.

Authors:  Vera S Schellerer; Lenka Bartholomé; Melanie C Langheinrich; Robert Grützmann; Raymund E Horch; Susanne Merkel; Klaus Weber
Journal:  World J Surg       Date:  2020-09-29       Impact factor: 3.352

  10 in total

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