Literature DB >> 14662398

Drug delivery in biotechnology: present and future.

Gorka Orive1, Rosa Maria Hernández, Alicia Rodríguez Gascón, Alfonso Domínguez-Gil, José Luis Pedraz.   

Abstract

Drug delivery is becoming a whole interdisciplinary and independent field of research and is gaining the attention of pharmaceutical makers, medical doctors and industry. A targeted and safe drug delivery could improve the performance of some classical medicines already on the market and, moreover, will have implications for the development and success of new therapeutic strategies, such as peptide and protein delivery, glycoprotein administration, gene therapy and RNA interference. Many innovative technologies for effective drug delivery have been developed, including implants, nanotechnology, cell and peptide encapsulation, microfabrication, chemical modification and others. On the long way from the clinic to market, however, several issues will have to be addressed, including suitable scientific development, specific financial support as a result of altered scientific policy, government regulations and market forces.

Mesh:

Year:  2003        PMID: 14662398     DOI: 10.1016/j.copbio.2003.10.007

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN: 0958-1669            Impact factor:   9.740


  26 in total

Review 1.  Drug delivery to the small intestine.

Authors:  David R Friend
Journal:  Curr Gastroenterol Rep       Date:  2004-10

2.  Coated microneedles for transdermal delivery.

Authors:  Harvinder S Gill; Mark R Prausnitz
Journal:  J Control Release       Date:  2006-10-24       Impact factor: 9.776

Review 3.  Nanomedicine: clinical applications of polyethylene glycol conjugated proteins and drugs.

Authors:  Suphiya Parveen; Sanjeeb K Sahoo
Journal:  Clin Pharmacokinet       Date:  2006       Impact factor: 6.447

4.  Preparation and evaluation of gene-transfected cultured skin as a novel drug delivery system for severely burned skin.

Authors:  Nobuko Hada; Hiroaki Todo; Fusao Komada; Kenji Sugibayashi
Journal:  Pharm Res       Date:  2007-03-22       Impact factor: 4.200

5.  Subcellular in vivo 1H MR spectroscopy of Xenopus laevis oocytes.

Authors:  Seung-Cheol Lee; Jee-Hyun Cho; Daniel Mietchen; Young-Sook Kim; Kwan Soo Hong; Chulhyun Lee; Dongmin Kang; Ki Deok Park; Byong-Seok Choi; Chaejoon Cheong
Journal:  Biophys J       Date:  2005-12-16       Impact factor: 4.033

Review 6.  Controlled delivery systems: from pharmaceuticals to cells and genes.

Authors:  Elizabeth Rosado Balmayor; Helena Sepulveda Azevedo; Rui L Reis
Journal:  Pharm Res       Date:  2011-03-19       Impact factor: 4.200

7.  Microbubble-mediated ultrasonic techniques for improved chemotherapeutic delivery in cancer.

Authors:  Anna G Sorace; Jason M Warram; Heidi Umphrey; Kenneth Hoyt
Journal:  J Drug Target       Date:  2011-10-10       Impact factor: 5.121

Review 8.  Combating malaria with nanotechnology-based targeted and combinatorial drug delivery strategies.

Authors:  Miloni Thakkar; Brijesh S
Journal:  Drug Deliv Transl Res       Date:  2016-08       Impact factor: 4.617

9.  Nanotechnology: an evidence-based analysis.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2006-11-01

10.  Optical fluorescent imaging to monitor temporal effects of microbubble-mediated ultrasound therapy.

Authors:  Anna G Sorace; Reshu Saini; Eben Rosenthal; Jason M Warram; Kurt R Zinn; Kenneth Hoyt
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2013-02       Impact factor: 2.725

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