Literature DB >> 14662388

Engineering of secondary metabolite pathways.

Benjamin N Mijts1, Claudia Schmidt-Dannert.   

Abstract

Nature produces an astonishing wealth of secondary metabolites with important biological functions. To access this diversity of structurally complex chemical compounds for industrial and biomedical applications, cells have been engineered to produce higher levels and/or novel compounds that were previously inaccessible. Recent examples of metabolic and combinatorial engineering illustrate different strategies for the production of secondary metabolites in microbial cells.

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Year:  2003        PMID： 14662388     DOI： 10.1016/j.copbio.2003.09.009

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN： 0958-1669            Impact factor:   9.740


  12 in total

Review 1.  Laboratory-directed protein evolution.

Authors:  Ling Yuan; Itzhak Kurek; James English; Robert Keenan
Journal:  Microbiol Mol Biol Rev       Date:  2005-09       Impact factor: 11.056

2.  Metabolic engineering of carotenoid biosynthesis in Escherichia coli by ordered gene assembly in Bacillus subtilis.

Authors:  Tomoko Nishizaki; Kenji Tsuge; Mitsuhiro Itaya; Nobuhide Doi; Hiroshi Yanagawa
Journal:  Appl Environ Microbiol       Date:  2006-12-28       Impact factor: 4.792

3.  Assessing in silico the recruitment and functional spectrum of bacterial enzymes from secondary metabolism.

Authors:  Valery Veprinskiy; Leonhard Heizinger; Maximilian G Plach; Rainer Merkl
Journal:  BMC Evol Biol       Date:  2017-01-26       Impact factor: 3.260

4.  Squalestatin is an inhibitor of carotenoid biosynthesis in Plasmodium falciparum.

Authors:  Heloisa B Gabriel; Marcia F Silva; Emília A Kimura; Gerhard Wunderlich; Alejandro M Katzin; Mauro F Azevedo
Journal:  Antimicrob Agents Chemother       Date:  2015-03-16       Impact factor: 5.191

5.  Biosynthesis of ubiquinone compounds with conjugated prenyl side chains.

Authors:  Pyung Cheon Lee; Christine Salomon; Benjamin Mijts; Claudia Schmidt-Dannert
Journal:  Appl Environ Microbiol       Date:  2008-09-26       Impact factor: 4.792

6.  High-level production of beta-carotene in Saccharomyces cerevisiae by successive transformation with carotenogenic genes from Xanthophyllomyces dendrorhous.

Authors:  René Verwaal; Jing Wang; Jean-Paul Meijnen; Hans Visser; Gerhard Sandmann; Johan A van den Berg; Albert J J van Ooyen
Journal:  Appl Environ Microbiol       Date:  2007-05-11       Impact factor: 4.792

7.  Carotenoid biosynthesis in intraerythrocytic stages of Plasmodium falciparum.

Authors:  Renata Tonhosolo; Fabio L D'Alexandri; Veridiana V de Rosso; Marcos L Gazarini; Miriam Y Matsumura; Valnice J Peres; Emilio F Merino; Jane M Carlton; Gerhard Wunderlich; Adriana Z Mercadante; Emília A Kimura; Alejandro M Katzin
Journal:  J Biol Chem       Date:  2009-02-09       Impact factor: 5.157

8.  Secondary metabolites as DNA topoisomerase inhibitors: A new era towards designing of anticancer drugs.

Authors:  Supriya Baikar; Nutan Malpathak
Journal:  Pharmacogn Rev       Date:  2010-01

9.  A tale of two reductases: extending the bacteriochlorophyll biosynthetic pathway in E. coli.

Authors:  Ilya B Tikh; Maureen B Quin; Claudia Schmidt-Dannert
Journal:  PLoS One       Date:  2014-02-21       Impact factor: 3.240

10.  Integer programming-based method for designing synthetic metabolic networks by Minimum Reaction Insertion in a Boolean model.

Authors:  Wei Lu; Takeyuki Tamura; Jiangning Song; Tatsuya Akutsu
Journal:  PLoS One       Date:  2014-03-20       Impact factor: 3.240
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