Literature DB >> 14661822

Sex-related differences in the length of disability prior to death in older persons.

Luigi Ferrucci1, Angela Turchi, Stefano Fumagalli, Mauro Di Bari, Gabriella Silvestrini, Simona Zacchei, Alessandra Nesti, Lorenza Magherini, Francesca Tarantini, Riccardo Pini, Enrico Antonini, Giulio Masotti, Niccolò Marchionni.   

Abstract

BACKGROUND AND AIMS: It is acknowledged that, in spite of their generally worse health, women live longer than men. However, whether women also enjoy longer disability-free lives is still unclear. Using data from a representative, Italian cohort followed for 6 years, this study aimed at estimating differences between men and women in the age of disability onset and in total survival.
METHODS: In 1989, 651 persons aged > or = 65 years were interviewed and their medical status was assessed by a geriatrician. In 1995, the time of onset of disability was reconstructed by re-interviewing 392 survivors and collecting proxy information for 201 subjects who had died. No information was available for 58 subjects who refused to be re-interviewed or were lost to follow-up. Data on changes in functional status were also collected by proxy interview for 34 additional persons who had died during the follow-up period, although they had not been originally interviewed at baseline.
RESULTS: Of the 235 deaths, 113 were men and 122 were women. On average, the age at death was 3.5 years higher among women than among men. However, the age at onset of disability was similar in the two sexes. In survival analysis in which age was the time variable, women were as likely as men to develop disability, but significantly less likely to die over the follow-up period.
CONCLUSIONS: Compared with men, women experience longer disability before death. This may be due to sex-related differences in the lifetime prevalence of lethal vs. disabling diseases.

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Year:  2003        PMID: 14661822     DOI: 10.1007/bf03324515

Source DB:  PubMed          Journal:  Aging Clin Exp Res        ISSN: 1594-0667            Impact factor:   3.636


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