Literature DB >> 146610

Type III (Arthus) allergic reactions and endotoxin toxicity in guinea-pigs.

A J McLean, J Dowling.   

Abstract

Lipoplysaccharide (endotoxin) from E. coli cells produced lethal effects in guinea-pigs. Endotoxin caused no visible dermal change in normal animals, but produced skin reactions characterized by specific Arthus-type (Type III immune hypersensitivity) vascular inflammation in immunized animals. It is concluded that Arthus allergic reactions were evoked by endotoxin, however, endotoxin lethal toxicity appears independent of this process.

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Year:  1978        PMID： 146610     DOI： 10.1007/bf01944701

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  9 in total

1.  MOTILITY-PROMOTING EFFECT OF THE BRUCELLA ABORTUS AND BRUCELLA MELITENSIS ENDOTOXIN ON THE SMOOTH UTERINE MUSCLE.

Authors:  B URBASCHEK
Journal:  Nature       Date:  1964-05-30       Impact factor: 49.962

2.  Mechanisms of the hemodynamic effects of endotoxin.

Authors:  R P GILBERT
Journal:  Physiol Rev       Date:  1960-04       Impact factor: 37.312

3.  Bacterial pyrogens.

Authors:  I L BENNETT; L E CLUFF
Journal:  Pharmacol Rev       Date:  1957-12       Impact factor: 25.468

4.  Hemodynamic measurements in bacteremia and septic shock in man.

Authors:  R M Gunnar; H S Loeb; E J Winslow; C Blain; J Robinson
Journal:  J Infect Dis       Date:  1973-07       Impact factor: 5.226

5.  Bacterial inhibition of ureteral smooth muscle contractility. I. The effect of common urinary pathogens and endotoxin in an in vitro system.

Authors:  W W King; C E Cox
Journal:  J Urol       Date:  1972-11       Impact factor: 7.450

6.  Recent experience with bacillemia due to gram-negative organisms.

Authors:  R L Myerowitz; A A Medeiros; T F O'Brien
Journal:  J Infect Dis       Date:  1971-09       Impact factor: 5.226

7.  Enteric flora of normal laboratory guinea-pigs.

Authors:  A J McLean; A Boquest
Journal:  Br J Exp Pathol       Date:  1977-06

8.  Anaphylactic reactions to endotoxin in guinea-pig tissues: relationship to endotoxin toxicity.

Authors:  A J McLean
Journal:  Br J Pharmacol       Date:  1977-07       Impact factor: 8.739

9.  Relationship between Escherichia coli endotoxin toxicity and the immunization status of normal adult guinea-pigs.

Authors:  A J McLean
Journal:  Br J Exp Pathol       Date:  1977-06
  9 in total

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