| Literature DB >> 14659676 |
Quanbin Zhang1, Ning Li, Xiguang Liu, Zengqin Zhao, Zhien Li, Zuhong Xu.
Abstract
The sulfated galactan fraction F1 isolated from the red seaweed, Porphyra haitanensis, showed typical porphyran structure. It has a linear backbone of alternating 3-linked beta-D-galactosyl units and 4-linked alpha-L-galactosyl 6-sulfate and 3,6-anhydro-alpha-L-galactosyl units. The L-residues are mainly composed of alpha-L-galactosyl 6-sulfate units, and the 3,6-anhydrogalactosyl units are minor. Partial methylation occurred at the C-6 position of the D-galactosyl units and at the C-2 position of the 3,6-anhydro-alpha-L-galactosyl units. Intraperitoneal administration of F1 significantly decreased the lipid peroxidation in aging mice. F1 treatment increased the total antioxidant capacity and the activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in aging mice. The results indicated that F1 had significant in vivo antioxidant activity.Entities:
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Year: 2004 PMID： 14659676 DOI： 10.1016/j.carres.2003.09.015
Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104