Literature DB >> 14658800

Isolation, structure elucidation and biological activities of trichofumins A, B, C and D, new 11 and 13mer peptaibols from Trichoderma sp. HKI 0276W.

Albrecht Berg1, Pavel A Grigoriev, Thomas Degenkolb, Torsten Neuhof, Albert Härtl, Brigitte Schlegel, Udo Gräfe.   

Abstract

Trichofumins A-D were isolated from cultures of Trichoderma sp. HKI 0276 as new 11 and 13mer peptaibols. Similar to 15mer peptaibols they promote morphogenesis of the fungus Phoma destructiva and cause hypothermia in mice as a characteristic of neuroleptic activity. Membrane measurements using a synthetic BLM model showed that A, B, C and D increased membrane permeability for cations in a similar manner as was shown for larger peptaibols but with comparably lower efficiency.

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Year:  2003        PMID： 14658800     DOI： 10.1002/psc.498

Source DB:  PubMed          Journal:  J Pept Sci        ISSN： 1075-2617            Impact factor:   1.905


  4 in total

1.  Two classes of new peptaibols are synthesized by a single non-ribosomal peptide synthetase of Trichoderma virens.

Authors:  Prasun K Mukherjee; Aric Wiest; Nicolas Ruiz; Andrew Keightley; Maria E Moran-Diez; Kevin McCluskey; Yves François Pouchus; Charles M Kenerley
Journal:  J Biol Chem       Date:  2010-12-01       Impact factor: 5.157

2.  Hypopulvins, novel peptaibiotics from the polyporicolous fungus Hypocrea pulvinata, are produced during infection of its natural hosts.

Authors:  Christian René Röhrich; Anita Iversen; Walter Michael Jaklitsch; Hermann Voglmayr; Albrecht Berg; Heinrich Dörfelt; Ulf Thrane; Andreas Vilcinskas; Kristian Fog Nielsen; Hans Von Döhren; Hans Brückner; Thomas Degenkolb
Journal:  Fungal Biol       Date:  2012-10-26

3.  Occurrence of filamentous fungi in Simulium goeldii Cerqueira & Nunes de Mello (diptera: simuliidae) larvae in central Amazonia, Brazil.

Authors:  Quézia Ribeiro Fonseca; Maria Inez de Moura Sarquis; Neusa Hamada; Yamile Benaion Alencar
Journal:  Braz J Microbiol       Date:  2008-06-01       Impact factor: 2.476

4.  Front line defenders of the ecological niche! Screening the structural diversity of peptaibiotics from saprotrophic and fungicolous Trichoderma/Hypocrea species.

Authors:  Christian R Röhrich; Walter M Jaklitsch; Hermann Voglmayr; Anita Iversen; Andreas Vilcinskas; Kristian Fog Nielsen; Ulf Thrane; Hans von Döhren; Hans Brückner; Thomas Degenkolb
Journal:  Fungal Divers       Date:  2014-11-01       Impact factor: 20.372
  4 in total

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