Literature DB >> 14657791

Molecular and cellular basis for anti-amyloid therapy in Alzheimer disease.

Sam Gandy1, Ralph N Martins, Joseph Buxbaum.   

Abstract

Entities:  

Mesh:

Substances:

Year:  2003        PMID: 14657791     DOI: 10.1097/00002093-200310000-00011

Source DB:  PubMed          Journal:  Alzheimer Dis Assoc Disord        ISSN: 0893-0341            Impact factor:   2.703


× No keyword cloud information.
  14 in total

Review 1.  The role of gonadotropins in Alzheimer's disease: potential neurodegenerative mechanisms.

Authors:  Anna M Barron; Giuseppe Verdile; Ralph N Martins
Journal:  Endocrine       Date:  2006-04       Impact factor: 3.633

2.  Changing the course of Alzheimer's disease: anti-amyloid disease-modifying treatments on the horizon.

Authors:  Daniel D Christensen
Journal:  Prim Care Companion J Clin Psychiatry       Date:  2007

3.  The cysteine protease inhibitor, E64d, reduces brain amyloid-β and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, β-secretase activity.

Authors:  Gregory Hook; Vivian Hook; Mark Kindy
Journal:  J Alzheimers Dis       Date:  2011       Impact factor: 4.472

Review 4.  Cysteine Cathepsins in the secretory vesicle produce active peptides: Cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's disease.

Authors:  Vivian Hook; Lydiane Funkelstein; Jill Wegrzyn; Steven Bark; Mark Kindy; Gregory Hook
Journal:  Biochim Biophys Acta       Date:  2011-09-08

5.  Beta-amyloid peptides undergo regulated co-secretion with neuropeptide and catecholamine neurotransmitters.

Authors:  Thomas Toneff; Lydiane Funkelstein; Charles Mosier; Armen Abagyan; Michael Ziegler; Vivian Hook
Journal:  Peptides       Date:  2013-06-06       Impact factor: 3.750

Review 6.  Brain activation of SIRT1: role in neuropathology.

Authors:  Alanna Fernandes Paraíso; Keila Lopes Mendes; Sergio Henrique Sousa Santos
Journal:  Mol Neurobiol       Date:  2013-04-25       Impact factor: 5.590

7.  Preventing formation of reticulon 3 immunoreactive dystrophic neurites improves cognitive function in mice.

Authors:  Qi Shi; Marguerite Prior; Xiangdong Zhou; Xiaoying Tang; Wanxia He; Xiangyou Hu; Riqiang Yan
Journal:  J Neurosci       Date:  2013-02-13       Impact factor: 6.167

8.  Brain pyroglutamate amyloid-β is produced by cathepsin B and is reduced by the cysteine protease inhibitor E64d, representing a potential Alzheimer's disease therapeutic.

Authors:  Gregory Hook; Jin Yu; Thomas Toneff; Mark Kindy; Vivian Hook
Journal:  J Alzheimers Dis       Date:  2014       Impact factor: 4.472

9.  Genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein.

Authors:  Vivian Y H Hook; Mark Kindy; Thomas Reinheckel; Christoph Peters; Gregory Hook
Journal:  Biochem Biophys Res Commun       Date:  2009-06-06       Impact factor: 3.575

Review 10.  Alternative pathways for production of beta-amyloid peptides of Alzheimer's disease.

Authors:  Vivian Hook; Israel Schechter; Hans-Ulrich Demuth; Gregory Hook
Journal:  Biol Chem       Date:  2008-08       Impact factor: 3.915

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.