Literature DB >> 14657652

A role for JNK-paxillin signaling in cell migration.

Cai Huang1, Ken Jacobson, Michael D Schaller.   

Abstract

Recently, we and others demonstrated that JNK is essential for cell migration in a number of cell types. We also showed that JNK phosphorylates serine 178 on paxillin, a focal adhesion adaptor, both in vitro and in vivo. Moreover, phosphorylation of Ser 178 on paxillin is essential for cell migration and involved in modulating cell adhesions. A model is proposed to depict the role of JNK-paxillin signaling in cell migration.

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Year:  2004        PMID： 14657652

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


  26 in total

1.  Paxillin and hydrogen peroxide-inducible clone 5 expression and distribution in control and Alzheimer disease hippocampi.

Authors:  John Caltagarone; Ronald L Hamilton; Geoffrey Murdoch; Zheng Jing; Donald B DeFranco; Robert Bowser
Journal:  J Neuropathol Exp Neurol       Date:  2010-04       Impact factor: 3.685

2.  MicroRNA-145 suppresses cell migration and invasion by targeting paxillin in human colorectal cancer cells.

Authors:  Jun Qin; Feiran Wang; Haiyan Jiang; Junfei Xu; Yasu Jiang; Zhiwei Wang
Journal:  Int J Clin Exp Pathol       Date:  2015-02-01

3.  Fluid shear stress-induced JNK activity leads to actin remodeling for cell alignment.

Authors:  Meron Mengistu; Hannah Brotzman; Samir Ghadiali; Linda Lowe-Krentz
Journal:  J Cell Physiol       Date:  2011-01       Impact factor: 6.384

4.  Loss of MLCK leads to disruption of cell-cell adhesion and invasive behavior of breast epithelial cells via increased expression of EGFR and ERK/JNK signaling.

Authors:  D Y Kim; D M Helfman
Journal:  Oncogene       Date:  2016-02-15       Impact factor: 9.867

5.  Activity of all JNK isoforms contributes to neurite growth in spiral ganglion neurons.

Authors:  Patrick J Atkinson; Chang-Hyun Cho; Marlan R Hansen; Steven H Green
Journal:  Hear Res       Date:  2011-05-01       Impact factor: 3.208

6.  Vibrio parahaemolyticus VopA Is a Potent Inhibitor of Cell Migration and Apoptosis in the Intestinal Epithelium of Drosophila melanogaster.

Authors:  Liping Luo; Jason D Matthews; Brian S Robinson; Rheinallt M Jones
Journal:  Infect Immun       Date:  2019-02-21       Impact factor: 3.441

7.  An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation.

Authors:  Carine Rosse; Etienne Formstecher; Katrina Boeckeler; Yingming Zhao; Joachim Kremerskothen; Michael D White; Jacques H Camonis; Peter J Parker
Journal:  PLoS Biol       Date:  2009-11-03       Impact factor: 8.029

8.  The beta1 integrin activates JNK independent of CagA, and JNK activation is required for Helicobacter pylori CagA+-induced motility of gastric cancer cells.

Authors:  Jared L Snider; Cody Allison; Bryan H Bellaire; Richard L Ferrero; James A Cardelli
Journal:  J Biol Chem       Date:  2008-03-20       Impact factor: 5.157

9.  Tissue transglutaminase is an essential participant in the epidermal growth factor-stimulated signaling pathway leading to cancer cell migration and invasion.

Authors:  Marc A Antonyak; Bo Li; Andrew D Regan; Qiyu Feng; Stephanie S Dusaban; Richard A Cerione
Journal:  J Biol Chem       Date:  2009-04-29       Impact factor: 5.157

10.  Ethanol exposure during neurogenesis induces persistent effects on neural maturation: evidence from an ex vivo model of fetal cerebral cortical neuroepithelial progenitor maturation.

Authors:  Cynthia Camarillo; Rajesh C Miranda
Journal:  Gene Expr       Date:  2008
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