Literature DB >> 14657347

MED1: a central molecule for maintenance of genome integrity and response to DNA damage.

Barbara L Parsons1.   

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Year:  2003        PMID： 14657347      PMCID： PMC299743          DOI： 10.1073/pnas.2637169100

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  16 in total

1.  Biphasic kinetics of the human DNA repair protein MED1 (MBD4), a mismatch-specific DNA N-glycosylase.

Authors:  F Petronzelli; A Riccio; G D Markham; S H Seeholzer; J Stoerker; M Genuardi; A T Yeung; Y Matsumoto; A Bellacosa
Journal:  J Biol Chem       Date:  2000-10-20       Impact factor: 5.157

2.  Mbd4 inactivation increases Cright-arrowT transition mutations and promotes gastrointestinal tumor formation.

Authors:  Edmund Wong; Kan Yang; Mari Kuraguchi; Uwe Werling; Elena Avdievich; Kunhua Fan; Melissa Fazzari; Bo Jin; Anthony M C Brown; Martin Lipkin; Winfried Edelmann
Journal:  Proc Natl Acad Sci U S A       Date:  2002-11-04       Impact factor: 11.205

Review 3.  Functional interactions and signaling properties of mammalian DNA mismatch repair proteins.

Authors:  A Bellacosa
Journal:  Cell Death Differ       Date:  2001-11       Impact factor: 15.828

4.  The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites.

Authors:  B Hendrich; U Hardeland; H H Ng; J Jiricny; A Bird
Journal:  Nature       Date:  1999-09-16       Impact factor: 49.962

5.  Investigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): fundamental role of the catalytic domain.

Authors:  F Petronzelli; A Riccio; G D Markham; S H Seeholzer; M Genuardi; M Karbowski; A T Yeung; Y Matsumoto; A Bellacosa
Journal:  J Cell Physiol       Date:  2000-12       Impact factor: 6.384

6.  5-Methylcytosine DNA glycosylase activity is also present in the human MBD4 (G/T mismatch glycosylase) and in a related avian sequence.

Authors:  B Zhu; Y Zheng; H Angliker; S Schwarz; S Thiry; M Siegmann; J P Jost
Journal:  Nucleic Acids Res       Date:  2000-11-01       Impact factor: 16.971

7.  Human DNA mismatch repair in vitro operates independently of methylation status at CpG sites.

Authors:  J T Drummond; A Bellacosa
Journal:  Nucleic Acids Res       Date:  2001-06-01       Impact factor: 16.971

8.  Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice.

Authors:  Catherine B Millar; Jacky Guy; Owen J Sansom; Jim Selfridge; Eilidh MacDougall; Brian Hendrich; Peter D Keightley; Stefan M Bishop; Alan R Clarke; Adrian Bird
Journal:  Science       Date:  2002-07-19       Impact factor: 47.728

Review 9.  DNA repair and tumorigenesis: lessons from hereditary cancer syndromes.

Authors:  Christopher D Heinen; Christoph Schmutte; Richard Fishel
Journal:  Cancer Biol Ther       Date:  2002 Sep-Oct       Impact factor: 4.742

Review 10.  DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis.

Authors:  Carol Bernstein; Harris Bernstein; Claire M Payne; Harinder Garewal
Journal:  Mutat Res       Date:  2002-06       Impact factor: 2.433
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  7 in total

1.  MBD4 and MLH1 are required for apoptotic induction in xDNMT1-depleted embryos.

Authors:  Alexey Ruzov; Boris Shorning; Oliver Mortusewicz; Donncha S Dunican; Heinrich Leonhardt; Richard R Meehan
Journal:  Development       Date:  2009-07       Impact factor: 6.868

2.  Is gastric cancer part of the tumour spectrum of hereditary non-polyposis colorectal cancer? A molecular genetic study.

Authors:  A Gylling; W M Abdel-Rahman; M Juhola; K Nuorva; E Hautala; H J Järvinen; J-P Mecklin; M Aarnio; P Peltomäki
Journal:  Gut       Date:  2007-01-31       Impact factor: 23.059

3.  Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer.

Authors:  J Harrison Howard; Andrey Frolov; Ching-Wei D Tzeng; Ashley Stewart; Andrew Midzak; Amar Majmundar; Andrew Godwin; Martin Heslin; Alfonso Bellacosa; J Pablo Arnoletti
Journal:  Cancer Biol Ther       Date:  2009-01-20       Impact factor: 4.742

4.  5-halogenated pyrimidine lesions within a CpG sequence context mimic 5-methylcytosine by enhancing the binding of the methyl-CpG-binding domain of methyl-CpG-binding protein 2 (MeCP2).

Authors:  Victoria Valinluck; Pingfang Liu; Joseph I Kang; Artur Burdzy; Lawrence C Sowers
Journal:  Nucleic Acids Res       Date:  2005-05-25       Impact factor: 16.971

5.  Reduced syncytin-1 expression levels in placental syndromes correlates with epigenetic hypermethylation of the ERVW-1 promoter region.

Authors:  Matthias Ruebner; Pamela L Strissel; Arif B Ekici; Elisabeth Stiegler; Ulf Dammer; Tamme W Goecke; Florian Faschingbauer; Fabian B Fahlbusch; Matthias W Beckmann; Reiner Strick
Journal:  PLoS One       Date:  2013-02-14       Impact factor: 3.240

6.  Involvement of MBD4 inactivation in mismatch repair-deficient tumorigenesis.

Authors:  Rossella Tricarico; Salvatore Cortellino; Antonio Riccio; Shantie Jagmohan-Changur; Heleen Van der Klift; Juul Wijnen; David Turner; Andrea Ventura; Valentina Rovella; Antonio Percesepe; Emanuela Lucci-Cordisco; Paolo Radice; Lucio Bertario; Monica Pedroni; Maurizio Ponz de Leon; Pietro Mancuso; Karthik Devarajan; Kathy Q Cai; Andres J P Klein-Szanto; Giovanni Neri; Pål Møller; Alessandra Viel; Maurizio Genuardi; Riccardo Fodde; Alfonso Bellacosa
Journal:  Oncotarget       Date:  2015-12-15

7.  Maftools: efficient and comprehensive analysis of somatic variants in cancer.

Authors:  Anand Mayakonda; De-Chen Lin; Yassen Assenov; Christoph Plass; H Phillip Koeffler
Journal:  Genome Res       Date:  2018-10-19       Impact factor: 9.043
  7 in total

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