Literature DB >> 14655806

Common problems in patients recovering from chemical dependency.

Edna Marie Jones1, Doug Knutson, Danell Haines.   

Abstract

Chemical dependency is a common, chronic disease that affects up to 25 percent of patients seen in primary care practices. The treatment goal for patients recovering from chemical dependency should be to avoid relapse. This requires physicians to have an open, nonjudgmental attitude and specific expertise about the implications of addiction for other health problems. First-line treatment for chemical dependency should be nonpharmacologic, but when medication is necessary, physicians should avoid drugs that have the potential for abuse or addiction. Medications that sedate or otherwise impair judgment also should be avoided in the recovering patient. Psychiatric illnesses should be aggressively treated, because untreated symptoms increase the risk of relapse into chemical dependency. Selective serotonin reuptake inhibitors may help to lower alcohol consumption in depressed patients, and desipramine may help to facilitate abstinence in persons addicted to cocaine. If insomnia extends beyond the acute or postacute withdrawal period, trazodone may be an effective treatment. If nonpharmacologic management of pain is not possible, nonaddictive medications should be used. However, if non-addictive medications fail, long-acting opiates used under strict supervision may be considered. Uncontrolled pain in itself is a relapse risk.

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Year:  2003        PMID: 14655806

Source DB:  PubMed          Journal:  Am Fam Physician        ISSN: 0002-838X            Impact factor:   3.292


  15 in total

1.  Corticostriatal Afferents Modulate Responsiveness to Psychostimulant Drugs and Drug-Associated Stimuli.

Authors:  K A Kerstetter; A M Wunsch; K G Nakata; E Donckels; J F Neumaier; Susan M Ferguson
Journal:  Neuropsychopharmacology       Date:  2015-08-20       Impact factor: 7.853

Review 2.  Depression research: where are we now?

Authors:  Saebom Lee; Jaehoon Jeong; Yongdo Kwak; Sang Ki Park
Journal:  Mol Brain       Date:  2010-03-10       Impact factor: 4.041

3.  Learned motivation drives circadian physiology in the absence of the master circadian clock.

Authors:  Oliver Rawashdeh; Shannon J Clough; Randall L Hudson; Margarita L Dubocovich
Journal:  FASEB J       Date:  2016-10-12       Impact factor: 5.191

4.  Free-running rhythms of cocaine self-administration in rats held under constant lighting conditions.

Authors:  Caroline E Bass; Heiko T Jansen; David C S Roberts
Journal:  Chronobiol Int       Date:  2010-05       Impact factor: 2.877

5.  Sleep and gambling severity in a community sample of gamblers.

Authors:  Iman Parhami; Aaron Siani; Richard J Rosenthal; Stephanie Lin; Michael Collard; Timothy W Fong
Journal:  J Addict Dis       Date:  2012

6.  The Brain's Reward System in Health and Disease.

Authors:  Robert G Lewis; Ermanno Florio; Daniela Punzo; Emiliana Borrelli
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

Review 7.  Circadian rhythms and addiction: mechanistic insights and future directions.

Authors:  Ryan W Logan; Wilbur P Williams; Colleen A McClung
Journal:  Behav Neurosci       Date:  2014-04-14       Impact factor: 1.912

Review 8.  A role for the circadian genes in drug addiction.

Authors:  Edgardo Falcón; Colleen A McClung
Journal:  Neuropharmacology       Date:  2008-07-03       Impact factor: 5.250

9.  Differential regulation of the period genes in striatal regions following cocaine exposure.

Authors:  Edgardo Falcon; Angela Ozburn; Shibani Mukherjee; Kole Roybal; Colleen A McClung
Journal:  PLoS One       Date:  2013-06-11       Impact factor: 3.240

Review 10.  Randomization in substance abuse clinical trials.

Authors:  Sarra L Hedden; Robert F Woolson; Robert J Malcolm
Journal:  Subst Abuse Treat Prev Policy       Date:  2006-02-06
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