Literature DB >> 146543

[The effect of Mn2+ on thyroid iodine metabolism in rats].

A M Buthieau, N Autissier.   

Abstract

Injection into rats of manganous chloride (2 mg/100 g) showed, after a 24-hr period, a marked depression of thyroidal 131I uptake. There is a decrease in serum T3 and T4 levels and an increase in I- level. These results demonstrate that the action of manganous ions is to block uptake of I- by the thyroid.

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Year:  1977        PMID: 146543

Source DB:  PubMed          Journal:  C R Seances Soc Biol Fil        ISSN: 0037-9026


  5 in total

1.  Deficiency in the manganese efflux transporter SLC30A10 induces severe hypothyroidism in mice.

Authors:  Steven Hutchens; Chunyi Liu; Thomas Jursa; William Shawlot; Beth K Chaffee; Weiling Yin; Andrea C Gore; Michael Aschner; Donald R Smith; Somshuvra Mukhopadhyay
Journal:  J Biol Chem       Date:  2017-05-01       Impact factor: 5.157

2.  Hypothyroidism induced by loss of the manganese efflux transporter SLC30A10 may be explained by reduced thyroxine production.

Authors:  Chunyi Liu; Steven Hutchens; Thomas Jursa; William Shawlot; Elena V Polishchuk; Roman S Polishchuk; Beth K Dray; Andrea C Gore; Michael Aschner; Donald R Smith; Somshuvra Mukhopadhyay
Journal:  J Biol Chem       Date:  2017-08-31       Impact factor: 5.157

3.  Hormonal control of manganese transport in the mouse thyroid.

Authors:  M Nishida; J Kawada
Journal:  Experientia       Date:  1992-03-15

4.  Effects of manganese ions on thyroid function in rat.

Authors:  A M Buthieau; N Autissier
Journal:  Arch Toxicol       Date:  1983-11       Impact factor: 5.153

5.  Effects of Sub-Acute Manganese Exposure on Thyroid Hormone and Glutamine (Gln)/Glutamate (Glu)-γ- Aminobutyric Acid (GABA) Cycle in Serum of Rats.

Authors:  Chao-Yan Ou; Yong-Hua He; Yi Sun; Lin Yang; Wen-Xiang Shi; Shao-Jun Li
Journal:  Int J Environ Res Public Health       Date:  2019-06-18       Impact factor: 3.390

  5 in total

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