Literature DB >> 14653686

Palladium-catalyzed regioselective arylation of imidazo[1,2-a]pyrimidine.

Wenjie Li1, Dorian P Nelson, Mark S Jensen, R Scott Hoerrner, Gary J Javadi, Dongwei Cai, Robert D Larsen.   

Abstract

Imidazo[1,2-a]pyrimidine can be arylated at the 3-position with aryl bromides in the presence of base and a catalytic amount of palladium. This provides an efficient one-step synthesis of 3-arylimidazo[1,2-a]pyrimidines from the unsubstituted heterocycle. [reaction: see text]

Entities:  

Year:  2003        PMID： 14653686     DOI： 10.1021/ol035878k

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  7 in total

Review 1.  Direct transition metal-catalyzed functionalization of heteroaromatic compounds.

Authors:  Ilya V Seregin; Vladimir Gevorgyan
Journal:  Chem Soc Rev       Date:  2007-03-05       Impact factor: 54.564

2.  Direct palladium-catalyzed alkynylation of N-fused heterocycles.

Authors:  Ilya V Seregin; Victoria Ryabova; Vladimir Gevorgyan
Journal:  J Am Chem Soc       Date:  2007-06-01       Impact factor: 15.419

3.  Palladium-Catalyzed Highly Regioselective C-3 Arylation of Imidazo[1,5-a]pyridine.

Authors:  Chunhui Huang; Alexandros Giokaris; Vladimir Gevorgyan
Journal:  Chem Lett       Date:  2011       Impact factor: 1.389

4.  2-Aminobenzimidazole derivatives strongly inhibit and disperse Pseudomonas aeruginosa biofilms.

Authors:  Reto Frei; Anthony S Breitbach; Helen E Blackwell
Journal:  Angew Chem Int Ed Engl       Date:  2012-04-05       Impact factor: 15.336

5.  Phosphine-free palladium-catalyzed C-H bond arylation of free (N-H)-indoles and pyrroles.

Authors:  Xiang Wang; Denis V Gribkov; Dalibor Sames
Journal:  J Org Chem       Date:  2007-02-16       Impact factor: 4.354

6.  Palladium-catalyzed arylation and heteroarylation of indolizines.

Authors:  Choul-Hong Park; Victoria Ryabova; Ilya V Seregin; Anna W Sromek; Vladimir Gevorgyan
Journal:  Org Lett       Date:  2004-04-01       Impact factor: 6.005

7.  Rh(I)-catalyzed arylation of heterocycles via C-H bond activation: expanded scope through mechanistic insight.

Authors:  Jared C Lewis; Ashley M Berman; Robert G Bergman; Jonathan A Ellman
Journal:  J Am Chem Soc       Date:  2008-02-02       Impact factor: 15.419
  7 in total

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