Literature DB >> 14652517

Prevalence of lower-limb ulceration: a systematic review of prevalence studies.

Ian D Graham1, Margaret B Harrison, E Andrea Nelson, Karen Lorimer, Andrea Fisher.   

Abstract

OBJECTIVE: To determine the prevalence of leg ulcers reported in the literature.
DESIGN: A systematic review of prevalence studies of lower-limb ulceration in the adult population was conducted. Critical appraisal of the research papers was guided by published standards for methodologic review of prevalence studies, which were modified to address the issues related to leg ulcers. MAIN
RESULTS: Twenty-two reports of prevalence studies were identified. Eight population-based prevalence studies used clinical validation and reported prevalence rates of open ulcers ranging from 0.12% to 1.1% of the population; the prevalence rate of open or healed ulcers was reported to be 1.8%. Seven population-based studies without clinical validation reported prevalence rates of open ulcers ranging from 0.12% to 0.32% of the population. Differences in the populations studied, study design, ulcer definition, ulcer etiology, inclusion of foot ulcers, method of clinical assessment, and clinical validation of ulcer cases indicate that it is inappropriate to pool the estimates of prevalence. In most studies that considered age and sex, the prevalence of ulcers increased with age and was higher for women.
CONCLUSIONS: Better-quality prevalence studies are needed. These studies should clearly define the populations being studied, include large numbers of individuals and total populations, provide a clear definition of an ulcer, describe case identification procedures, and clinically confirm the presence of ulcers.

Entities:  

Mesh:

Year:  2003        PMID: 14652517     DOI: 10.1097/00129334-200311000-00013

Source DB:  PubMed          Journal:  Adv Skin Wound Care        ISSN: 1527-7941            Impact factor:   2.347


  60 in total

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3.  The effects of education and training on clinical practice in wound healing.

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4.  Dehydrated Amniotic Membrane Allograft for Treatment of Chronic Leg Ulcers in Patients With Multiple Comorbidities: A Case Series.

Authors:  Stephen M Barr
Journal:  J Am Coll Clin Wound Spec       Date:  2016-02-04

5.  Can different primary care databases produce comparable estimates of burden of disease: results of a study exploring venous leg ulceration.

Authors:  Emily S Petherick; Kate E Pickett; Nicky A Cullum
Journal:  Fam Pract       Date:  2015-05-01       Impact factor: 2.267

6.  Clinical Evaluation of a Novel Topical Negative Pressure Device in Promoting Healing in Chronic Wounds.

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Journal:  Adv Wound Care (New Rochelle)       Date:  2015-06-01       Impact factor: 4.730

Review 7.  Current and Emerging Topical Antibacterials and Antiseptics: Agents, Action, and Resistance Patterns.

Authors:  Deborah A Williamson; Glen P Carter; Benjamin P Howden
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Review 8.  Preventing venous ulcer recurrence: a review.

Authors:  Kathryn R Vowden; Peter Vowden
Journal:  Int Wound J       Date:  2006-03       Impact factor: 3.315

9.  Aetiology, comorbidities and cofactors of chronic leg ulcers: retrospective evaluation of 1 000 patients from 10 specialised dermatological wound care centers in Germany.

Authors:  Finja Jockenhöfer; Harald Gollnick; Katharina Herberger; Georg Isbary; Regina Renner; Markus Stücker; Eva Valesky; Uwe Wollina; Michael Weichenthal; Sigrid Karrer; Bernhard Kuepper; Alexander Roesch; Joachim Dissemond
Journal:  Int Wound J       Date:  2014-12-05       Impact factor: 3.315

10.  Negative pressure wound therapy: an evidence-based analysis.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2006-07-01
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