Literature DB >> 14651111

Total synthesis of (-)-raumacline.

Patrick D Bailey1, Paul D Clingan, Timothy J Mills, Richard A Price, Robin G Pritchard.   

Abstract

The total synthesis of (-)-raumacline from L-tryptophan was achieved, featuring a cis-specific Pictet-Spengler reaction, a stereoselective Dieckmann cyclization, and an epimerization step that allowed complete stereocontrol of five chiral centres.

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Year:  2003        PMID: 14651111     DOI: 10.1039/b310274b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

Review 1.  The Chiral Pool in the Pictet-Spengler Reaction for the Synthesis of β-Carbolines.

Authors:  Renato Dalpozzo
Journal:  Molecules       Date:  2016-05-27       Impact factor: 4.411

  1 in total

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