Literature DB >> 14651102

Evidence from engineered gene fusions for the repeated use of a module in a modular polyketide synthase.

Carlos Olano1, Barrie Wilkinson, Steven J Moss, Alfredo F Braña, Carmen Méndez, Peter F Leadlay, José A Salas.   

Abstract

Functional evidence for programmed loss of co-linearity on the borrelidin modular polyketide synthase (PKS) is presented.

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Substances:

Year:  2003        PMID: 14651102     DOI: 10.1039/b310648a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  10 in total

1.  Reprogramming a module of the 6-deoxyerythronolide B synthase for iterative chain elongation.

Authors:  Shiven Kapur; Brian Lowry; Satoshi Yuzawa; Sanketha Kenthirapalan; Alice Y Chen; David E Cane; Chaitan Khosla
Journal:  Proc Natl Acad Sci U S A       Date:  2012-02-27       Impact factor: 11.205

2.  Interrogating the molecular basis for multiple macrolactone ring formation by the pikromycin polyketide synthase.

Authors:  Jeffrey D Kittendorf; Brian J Beck; Tonia J Buchholz; Wolfgang Seufert; David H Sherman
Journal:  Chem Biol       Date:  2007-08

3.  Functional dissection of a multimodular polypeptide of the pikromycin polyketide synthase into monomodules by using a matched pair of heterologous docking domains.

Authors:  John Yan; Shuchi Gupta; David H Sherman; Kevin A Reynolds
Journal:  Chembiochem       Date:  2009-06-15       Impact factor: 3.164

4.  Iterative Mechanism of Macrodiolide Formation in the Anticancer Compound Conglobatin.

Authors:  Yongjun Zhou; Annabel C Murphy; Markiyan Samborskyy; Patricia Prediger; Luiz Carlos Dias; Peter F Leadlay
Journal:  Chem Biol       Date:  2015-06-18

Review 5.  Molecular insights on the biosynthesis of antitumour compounds by actinomycetes.

Authors:  Carlos Olano; Carmen Méndez; José A Salas
Journal:  Microb Biotechnol       Date:  2010-11-18       Impact factor: 5.813

6.  An Iterative Module in the Azalomycin F Polyketide Synthase Contains a Switchable Enoylreductase Domain.

Authors:  Wei Xu; Guifa Zhai; Yuanzhen Liu; Yuan Li; Yanrong Shi; Kui Hong; Hui Hong; Peter F Leadlay; Zixin Deng; Yuhui Sun
Journal:  Angew Chem Int Ed Engl       Date:  2017-04-18       Impact factor: 15.336

7.  The biosynthetic pathway to ossamycin, a macrocyclic polyketide bearing a spiroacetal moiety.

Authors:  Oksana Bilyk; Markiyan Samborskyy; Peter F Leadlay
Journal:  PLoS One       Date:  2019-04-30       Impact factor: 3.240

Review 8.  Reviewing a plethora of oxidative-type reactions catalyzed by whole cells of Streptomyces species.

Authors:  Sara Salama; Mohamed H Habib; Rajni Hatti-Kaul; Yasser Gaber
Journal:  RSC Adv       Date:  2022-03-01       Impact factor: 3.361

9.  Novel intermolecular iterative mechanism for biosynthesis of mycoketide catalyzed by a bimodular polyketide synthase.

Authors:  Tarun Chopra; Srijita Banerjee; Sarika Gupta; Gitanjali Yadav; Swadha Anand; Avadhesha Surolia; Rajendra P Roy; Debasisa Mohanty; Rajesh S Gokhale
Journal:  PLoS Biol       Date:  2008-07-08       Impact factor: 8.029

10.  Identification of a biosynthetic gene cluster for the polyene macrolactam sceliphrolactam in a Streptomyces strain isolated from mangrove sediment.

Authors:  Zhen Jie Low; Li Mei Pang; Yichen Ding; Qing Wei Cheang; Kim Le Mai Hoang; Hoa Thi Tran; Jinming Li; Xue-Wei Liu; Yoganathan Kanagasundaram; Liang Yang; Zhao-Xun Liang
Journal:  Sci Rep       Date:  2018-01-25       Impact factor: 4.379

  10 in total

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