Literature DB >> 14649784

Plasma ghrelin levels and malnutrition: a comparison of two etiologies.

M Krsek1, M Rosická, H Papezová, J Krízová, E Kotrlíková, M Haluz'k, V Justová, Z Lacinová, Z Jarkovská.   

Abstract

Ghrelin is a peptide hormone that is involved in regulating growth hormone secretion as well as food intake and energy homeostasis. The aim of this study was to compare changes in plasma ghrelin levels in patients with malnutrition due to anorexia nervosa (AN) or short bowel syndrome (SBS). Blood samples for laboratory analyses were taken from 16 AN patients (plus 13 comparable healthy controls) and 27 SBS patients (plus 13 comparable healthy controls) after an overnight fast. In comparison with their respective control groups, plasma ghrelin levels were increased in the AN patients (p < 0.05) and significantly decreased in the patients with SBS (p < 0.01). These results suggest that quantitative ghrelin secretion in the gut wall is important in determining ghrelin concentrations in the systemic circulation.

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Year:  2003        PMID： 14649784     DOI： 10.1007/bf03325015

Source DB:  PubMed          Journal:  Eat Weight Disord        ISSN： 1124-4909            Impact factor:   4.652


  19 in total

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Authors:  M Tschöp; D L Smiley; M L Heiman
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4.  Growth hormone secretagogue binding sites in peripheral human tissues.

Authors:  M Papotti; C Ghè; P Cassoni; F Catapano; R Deghenghi; E Ghigo; G Muccioli
Journal:  J Clin Endocrinol Metab       Date:  2000-10       Impact factor: 5.958

5.  The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion.

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Journal:  Endocrinology       Date:  2000-11       Impact factor: 4.736

6.  Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans.

Authors:  Y Date; M Kojima; H Hosoda; A Sawaguchi; M S Mondal; T Suganuma; S Matsukura; K Kangawa; M Nakazato
Journal:  Endocrinology       Date:  2000-11       Impact factor: 4.736

7.  Ghrelin is a growth-hormone-releasing acylated peptide from stomach.

Authors:  M Kojima; H Hosoda; Y Date; M Nakazato; H Matsuo; K Kangawa
Journal:  Nature       Date:  1999-12-09       Impact factor: 49.962

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Authors:  M Tschöp; C Weyer; P A Tataranni; V Devanarayan; E Ravussin; M L Heiman
Journal:  Diabetes       Date:  2001-04       Impact factor: 9.461

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Authors:  H Ariyasu; K Takaya; T Tagami; Y Ogawa; K Hosoda; T Akamizu; M Suda; T Koh; K Natsui; S Toyooka; G Shirakami; T Usui; A Shimatsu; K Doi; H Hosoda; M Kojima; K Kangawa; K Nakao
Journal:  J Clin Endocrinol Metab       Date:  2001-10       Impact factor: 5.958

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Journal:  Biochem Biophys Res Commun       Date:  2001-01-26       Impact factor: 3.575
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  6 in total

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Journal:  Obesity (Silver Spring)       Date:  2013-09-10       Impact factor: 5.002

Review 2.  The ghrelin/GOAT/GHS-R system and energy metabolism.

Authors:  Chung Thong Lim; Blerina Kola; Márta Korbonits
Journal:  Rev Endocr Metab Disord       Date:  2011-09       Impact factor: 6.514

3.  Fasting ghrelin is related to skeletal muscle mass in healthy adults.

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Journal:  Front Endocrinol (Lausanne)       Date:  2013-02-26       Impact factor: 5.555

5.  Ghrelin, via corticotropin-releasing factor receptors, reduces glucose uptake and increases lipid content in mouse myoblasts cells.

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Journal:  Physiol Rep       Date:  2021-01

6.  A Systematic Review and Meta-Analysis Finds Increased Blood Levels of All Forms of Ghrelin in Both Restricting and Binge-Eating/Purging Subtypes of Anorexia Nervosa.

Authors:  Maria Seidel; Signe Markmann Jensen; Darren Healy; Aakriti Dureja; Hunna J Watson; Birgitte Holst; Cynthia M Bulik; Jan Magnus Sjögren
Journal:  Nutrients       Date:  2021-02-23       Impact factor: 5.717
  6 in total

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