Literature DB >> 14648332

Fulminant meningococcemia and acute renal failure in a 3-year-old boy.

Ipek Akil1, Hasan Yüksel, Senol Coskun, Dilek Yilmaz, Ali Onag.   

Abstract

Acute renal failure is a common occurrence in sepsis, but is rarely reported in meningococcemia. We present a young child diagnosed with fulminant meningococcemia who had several poor prognostic factors, including hypotension, thrombocytopenia, purpura fulminans, seizures, the absence of meningitis with meningococcemia, and acute renal failure, which was successfully treated with peritoneal dialysis. Peritoneal dialysis was started on the 5th day because the patient had been anuric for 48 h. At that time, analysis showed that the child was both hypokalemic and hypophosphatemic. His serum blood urea nitrogen was 61 mg/dl, creatinine 2.75 mg/dl, potassium 2.8 mEq/l, and phosphorus 0.7 mg/dl. Urine output began on the 12th day post admission and normalization of serum creatinine was achieved on the 26th day. In conclusion, renal failure is an important complication of meningococcemia and, to be effective, sometimes long-term peritoneal dialysis is required. Profound metabolic abnormalities, such as hypokalemia and hypophosphatemia, may occur paradoxically in the presence of oliguria.

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Year:  2003        PMID: 14648332     DOI: 10.1007/s00467-003-1345-4

Source DB:  PubMed          Journal:  Pediatr Nephrol        ISSN: 0931-041X            Impact factor:   3.714


  11 in total

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9.  Endotoxemia stimulates skeletal muscle Na+-K+-ATPase and raises blood lactate under aerobic conditions in humans.

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  2 in total

1.  Hypophosphatemia in meningococcal sepsis.

Authors:  Charalampos Antachopoulos; Ioannis Papassotiriou
Journal:  Pediatr Nephrol       Date:  2004-12       Impact factor: 3.714

2.  Acute kidney injury in a mouse model of meningococcal disease.

Authors:  Karin R Kolbe; Talita R Sanches; Camilla Fanelli; Margoth R Garnica; Letícia Urbano de Castro; Karen Gooch; Stephen Thomas; Stephen Taylor; Andrew Gorringe; Irene de L Noronha; Lucia Andrade
Journal:  Int J Immunopathol Pharmacol       Date:  2021 Jan-Dec       Impact factor: 3.219

  2 in total

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