| Literature DB >> 14647235 |
M Boyce1, A Degterev, J Yuan.
Abstract
Caspases are a family of cysteine proteases homologous to the Caenorhabditis elegans programmed cell death gene product CED-3. Caspases and their distant relatives, meta- and paracaspases, have been found in phylogenetically distant nonmetazoan groups, including plants, fungi and prokaryotes. This review summarizes the current information on the mechanisms and functions of non-mammalian caspases and their relatives in apoptotic and nonapoptotic processes, and explores the possible evolutionary origin of the caspase family.Entities:
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Year: 2004 PMID: 14647235 DOI: 10.1038/sj.cdd.4401339
Source DB: PubMed Journal: Cell Death Differ ISSN: 1350-9047 Impact factor: 15.828