Sean D Adrean1, Ivan R Schwab. 1. Department of Ophthalmology, School of Medicine, University of California, Davis, California 95817, USA.
Abstract
PURPOSE: To document a case of central retinal vein occlusion (CRVO) associated with renal cell carcinoma and elevated levels of anticardiolipin and antiphospholipid antibodies. DESIGN: Observational case report. METHODS: History, clinical examination, chart review, and laboratory serologies were performed on a 63-year-old man with renal cell carcinoma with a 6-week history of decreased vision in his left eye. RESULTS: Vision was 20/40 in the left eye. Dilated fundus examination revealed a CRVO. Laboratory serologies revealed markedly elevated levels of anticardiolipin and antiphospholipid antibodies. CONCLUSION: This case illustrates an association between CRVO and renal cell carcinoma. A paraneoplastic process, consisting of both antiphospholipid and anticardiolipin antibodies, may be a mechanism for CRVO.
PURPOSE: To document a case of central retinal vein occlusion (CRVO) associated with renal cell carcinoma and elevated levels of anticardiolipin and antiphospholipid antibodies. DESIGN: Observational case report. METHODS: History, clinical examination, chart review, and laboratory serologies were performed on a 63-year-old man with renal cell carcinoma with a 6-week history of decreased vision in his left eye. RESULTS: Vision was 20/40 in the left eye. Dilated fundus examination revealed a CRVO. Laboratory serologies revealed markedly elevated levels of anticardiolipin and antiphospholipid antibodies. CONCLUSION: This case illustrates an association between CRVO and renal cell carcinoma. A paraneoplastic process, consisting of both antiphospholipid and anticardiolipin antibodies, may be a mechanism for CRVO.