Literature DB >> 14644191

Mitotic mechanics: the auroras come into view.

Paul D Andrews1, Elena Knatko, William J Moore, Jason R Swedlow.   

Abstract

Aurora kinases have recently taken centre stage in the regulation of key cell cycle processes. Aurora A is emerging as a critical regulator of centrosome and spindle function. Aurora B mediates chromosome segregation by ensuring proper biorientation of sister chromatids, possibly through the regulation of microtubule dynamics. This enzyme also functions in cytokinesis apparently by interacting with a critical GTPase and a kinesin-like protein. Recent work on both kinases has revealed functional links between Aurora kinase activity and the mechanics of cell division.

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Year:  2003        PMID： 14644191     DOI： 10.1016/j.ceb.2003.10.013

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  91 in total

1.  Spatial and temporal regulation of Condensins I and II in mitotic chromosome assembly in human cells.

Authors:  Takao Ono; Yuda Fang; David L Spector; Tatsuya Hirano
Journal:  Mol Biol Cell       Date:  2004-05-14       Impact factor: 4.138

Review 2.  Chromosomal passengers: the four-dimensional regulation of mitotic events.

Authors:  Paola Vagnarelli; William C Earnshaw
Journal:  Chromosoma       Date:  2004-09-04       Impact factor: 4.316

3.  Differentiation of cytoplasmic and meiotic spindle assembly MCAK functions by Aurora B-dependent phosphorylation.

Authors:  Ryoma Ohi; Tanuj Sapra; Jonathan Howard; Timothy J Mitchison
Journal:  Mol Biol Cell       Date:  2004-04-02       Impact factor: 4.138

4.  Role of survivin phosphorylation by aurora B in mitosis.

Authors:  Marlène Delacour-Larose; My-Nhung Hoang Thi; Stefan Dimitrov; Annie Molla
Journal:  Cell Cycle       Date:  2007-05-21       Impact factor: 4.534

5.  Aurora kinase inhibitor ZM447439 blocks chromosome-induced spindle assembly, the completion of chromosome condensation, and the establishment of the spindle integrity checkpoint in Xenopus egg extracts.

Authors:  Bedrick B Gadea; Joan V Ruderman
Journal:  Mol Biol Cell       Date:  2004-12-22       Impact factor: 4.138

Review 6.  Chromosome bi-orientation on the mitotic spindle.

Authors:  Tomoyuki U Tanaka
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2005-03-29       Impact factor: 6.237

7.  The C. elegans Tousled-like kinase contributes to chromosome segregation as a substrate and regulator of the Aurora B kinase.

Authors:  Zhenbo Han; Gary M Riefler; Jennifer R Saam; Susan E Mango; Jill M Schumacher
Journal:  Curr Biol       Date:  2005-05-24       Impact factor: 10.834

8.  Aurora-A kinase is essential for bipolar spindle formation and early development.

Authors:  Dale O Cowley; Jaime A Rivera-Pérez; Mark Schliekelman; Yizhou Joseph He; Trudy G Oliver; Lucy Lu; Ryan O'Quinn; E D Salmon; Terry Magnuson; Terry Van Dyke
Journal:  Mol Cell Biol       Date:  2008-12-15       Impact factor: 4.272

Review 9.  Chromatin-modifying enzymes as therapeutic targets--Part 2.

Authors:  Brian R Keppler; Trevor K Archer
Journal:  Expert Opin Ther Targets       Date:  2008-11       Impact factor: 6.902

10.  An Afg2/Spaf-related Cdc48-like AAA ATPase regulates the stability and activity of the C. elegans Aurora B kinase AIR-2.

Authors:  Todd R Heallen; Henry P Adams; Tokiko Furuta; Koen J Verbrugghe; Jill M Schumacher
Journal:  Dev Cell       Date:  2008-10       Impact factor: 12.270
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