Literature DB >> 14643908

Tacrolimus hydrate (FK506): therapeutic effects and selection of responders in the treatment of myasthenia gravis.

Nobuo Wakata1, Toyokazu Saito, Sachiko Tanaka, Toshihiko Hirano, Kitaro Oka.   

Abstract

Tacrolimus hydrate (FK506) reduces myasthenic symptoms due to its immunosuppressive properties. We studied the therapeutic effects of FK506 and noted improvement in 7 of 13 myasthenic patients on the clinical muscle test (myasthenia gravis, MG score). Two other patients with relapsing ocular symptoms improved. We also examined patient sensitivity to FK506, but could not predict such sensitivity before FK506 treatment in the present study.

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Year:  2003        PMID: 14643908     DOI: 10.1016/s0303-8467(03)00046-5

Source DB:  PubMed          Journal:  Clin Neurol Neurosurg        ISSN: 0303-8467            Impact factor:   1.876


  4 in total

1.  Quality of life and life circumstances in German myasthenia gravis patients.

Authors:  Sabine Twork; Susanne Wiesmeth; Jörg Klewer; Dieter Pöhlau; Joachim Kugler
Journal:  Health Qual Life Outcomes       Date:  2010-11-11       Impact factor: 3.186

Review 2.  Efficacy and safety of tacrolimus for myasthenia gravis: a systematic review and meta-analysis.

Authors:  Liang Wang; Suxian Zhang; Jianying Xi; Wenhui Li; Lei Zhou; Jun Lu; Jiahong Lu; Tiansong Zhang; Chongbo Zhao
Journal:  J Neurol       Date:  2017-09-18       Impact factor: 4.849

Review 3.  Efficacy and Safety of Tacrolimus in Myasthenia Gravis: A Systematic Review and Meta-analysis.

Authors:  Zuojie Zhang; Chunsong Yang; Lingli Zhang; Qiusha Yi; Zilong Hao
Journal:  Ann Indian Acad Neurol       Date:  2017 Oct-Dec       Impact factor: 1.383

4.  Favorable Effects of Tacrolimus Monotherapy on Myasthenia Gravis Patients.

Authors:  Zhirong Fan; Zunbo Li; Faxiu Shen; Xueping Zhang; Lin Lei; Shengyao Su; Yan Lu; Li Di; Min Wang; Min Xu; Yuwei Da
Journal:  Front Neurol       Date:  2020-10-27       Impact factor: 4.003

  4 in total

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