| Literature DB >> 14643468 |
Raymond P Kesner1, Michael E Ragozzino.
Abstract
In order to test an attribute specificity model of prefrontal cortex function, rats with lesions in the prelimbic-infralimbic (PL-IL) or anterior cingulate and precentral (AC-PC) subregions of the medial prefrontal cortex and controls were trained on an object-place paired associate task. Rats with AC-PC lesions acquired the task as readily as controls. In contrast, the PL-IL lesioned rats did not learn the task. Whenever higher order processing is required to solve a task, the data support an attribute-specificity model of prefrontal cortex function in that the PL-IL cortices support both object and place attribute information in a variety of tasks including object-place paired associate learning.Entities:
Mesh:
Year: 2003 PMID: 14643468 DOI: 10.1016/j.bbr.2003.09.024
Source DB: PubMed Journal: Behav Brain Res ISSN: 0166-4328 Impact factor: 3.332