| Literature DB >> 14643350 |
F P Bymaster1, E E Beedle, J Findlay, P T Gallagher, J H Krushinski, S Mitchell, D W Robertson, D C Thompson, L Wallace, D T Wong.
Abstract
A series of naphthalenyloxy-arylpropylamines have been prepared and are demonstrated to be inhibitors of both serotonin and norepinephrine reuptake. One member of this series, duloxetine (Cymbalta) has proven to be effective in clinical trials for the treatment of depression.Entities:
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Year: 2003 PMID： 14643350 DOI： 10.1016/j.bmcl.2003.08.079
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823