| Literature DB >> 14643349 |
David Egron1, Christian Périgaud, Gilles Gosselin, Anne-Marie Aubertin, Abdesslem Faraj, Majid Sélouane, Denis Postel, Christophe Len.
Abstract
The detailed study of the 1,3-dihydrobenzo[c]furan derivative of thymine is reported. The lack of anti-HIV activity of this compound in cell culture experiments is shown to be related to the inability of the corresponding 5'-triphosphate derivative to interact efficiently with the reverse transcriptase.Entities:
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Year: 2003 PMID： 14643349 DOI： 10.1016/j.bmcl.2003.09.031
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823