Literature DB >> 14643340

Design and syntheses of melanocortin subtype-4 receptor agonists: evolution of the pyridazinone archetype.

Feroze Ujjainwalla1, Daniel Warner, Thomas F Walsh, Matthew J Wyvratt, Changyou Zhou, Lihu Yang, Rubana N Kalyani, Tanya MacNeil, Lex H T Van der Ploeg, Charles I Rosenblum, Rui Tang, Aurawan Vongs, David H Weinberg, Mark T Goulet.   

Abstract

The discovery and optimization of a new class of non-peptidyl, pyridazinone derived melanocortin subtype-4 receptor agonists is disclosed.

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Year:  2003        PMID： 14643340     DOI： 10.1016/j.bmcl.2003.09.026

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

1.  Interactions of human melanocortin 4 receptor with nonpeptide and peptide agonists.

Authors:  Irina D Pogozheva; Biao-Xin Chai; Andrei L Lomize; Tung M Fong; David H Weinberg; Ravi P Nargund; Michael W Mulholland; Ira Gantz; Henry I Mosberg
Journal:  Biochemistry       Date:  2005-08-30       Impact factor: 3.162

2.  Synthesis and Structure-Activity Relationships of Substituted Urea Derivatives on Mouse Melanocortin Receptors.

Authors:  Anamika Singh; Johannes Kast; Marvin L S Dirain; Huisuo Huang; Carrie Haskell-Luevano
Journal:  ACS Chem Neurosci       Date:  2015-12-24       Impact factor: 4.418

Review 3.  Design, synthesis and biological evaluation of ligands selective for the melanocortin-3 receptor.

Authors:  Victor J Hruby; Minying Cai; James P Cain; Alexander V Mayorov; Matthew M Dedek; Devendra Trivedi
Journal:  Curr Top Med Chem       Date:  2007       Impact factor: 3.295
  3 in total

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