Literature DB >> 14643338

Binding of beta-carbolines at 5-HT(2) serotonin receptors.

Brian Grella1, Milt Teitler, Carol Smith, Katharine Herrick-Davis, R A Glennon.   

Abstract

A series of ring-substituted (i.e., methoxy and bromo) 3,4-dihydro- and 1,2,3,4-tetrahydro-beta-carbolines was examined at 5-HT(2A) and 5-HT(2C) serotonin receptors. Whereas most of the methoxy-substituted derivatives typically displayed affinities similar to their unsubstituted parents, certain (particularly 8-substituted) bromo derivatives displayed enhanced affinity. A binding profile was obtained for selected beta-carbolines.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 14643338     DOI： 10.1016/j.bmcl.2003.09.027

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  9 in total

Review 1.  N,N-dimethyltryptamine and Amazonian ayahuasca plant medicine.

Authors:  Edward James; Joachim Keppler; Thomas L Robertshaw; Ben Sessa
Journal:  Hum Psychopharmacol       Date:  2022-02-17       Impact factor: 2.130

2.  Acute Biphasic Effects of Ayahuasca.

Authors:  Eduardo Ekman Schenberg; João Felipe Morel Alexandre; Renato Filev; Andre Mascioli Cravo; João Ricardo Sato; Suresh D Muthukumaraswamy; Maurício Yonamine; Marian Waguespack; Izabela Lomnicka; Steven A Barker; Dartiu Xavier da Silveira
Journal:  PLoS One       Date:  2015-09-30       Impact factor: 3.240

3.  Development of a mechanism-based pharmacokinetic/pharmacodynamic model to characterize the thermoregulatory effects of serotonergic drugs in mice.

Authors:  Xi-Ling Jiang; Hong-Wu Shen; Donald E Mager; Stephan Schmidt; Ai-Ming Yu
Journal:  Acta Pharm Sin B       Date:  2016-08-06       Impact factor: 11.413

4.  It's Tea Time: Interference of Ayahuasca Brew on Discriminative Learning in Zebrafish.

Authors:  Bruno Lobao-Soares; Paulianny Eduardo-da-Silva; Hugo Amarilha; Jaquelinne Pinheiro-da-Silva; Priscila F Silva; Ana Carolina Luchiari
Journal:  Front Behav Neurosci       Date:  2018-08-27       Impact factor: 3.558

5.  Dehydrocrenatidine Inhibits Voltage-Gated Sodium Channels and Ameliorates Mechanic Allodia in a Rat Model of Neuropathic Pain.

Authors:  Fang Zhao; Qinglian Tang; Jian Xu; Shuangyan Wang; Shaoheng Li; Xiaohan Zou; Zhengyu Cao
Journal:  Toxins (Basel)       Date:  2019-04-18       Impact factor: 4.546

6.  The pharmacological interaction of compounds in ayahuasca: a systematic review.

Authors:  Simon Ruffell; Nige Netzband; Catherine Bird; Allan H Young; Mario F Juruena
Journal:  Braz J Psychiatry       Date:  2020 Nov-Dec       Impact factor: 2.697

7.  Cortisol Modulation by Ayahuasca in Patients With Treatment Resistant Depression and Healthy Controls.

Authors:  Ana C de Menezes Galvão; Raíssa N de Almeida; Erick A Dos Santos Silva; Fúlvio A M Freire; Fernanda Palhano-Fontes; Heloisa Onias; Emerson Arcoverde; João P Maia-de-Oliveira; Dráulio B de Araújo; Bruno Lobão-Soares; Nicole L Galvão-Coelho
Journal:  Front Psychiatry       Date:  2018-05-08       Impact factor: 4.157

Review 8.  Antidepressive and anxiolytic effects of ayahuasca: a systematic literature review of animal and human studies.

Authors:  Rafael G Dos Santos; Flávia L Osório; José Alexandre S Crippa; Jaime E C Hallak
Journal:  Braz J Psychiatry       Date:  2016-03       Impact factor: 2.697

9.  Synergistic antidepressant- and anxiolytic-like effects of harmaline along with cinanserin in acute restraint stress-treated mice.

Authors:  Sajedeh Mosaffa; Hanieh Ahmadi; Fatemeh Khakpai; Mohaddeseh Ebrahimi-Ghiri; Mohammad-Reza Zarrindast
Journal:  Psychopharmacology (Berl)       Date:  2020-11-14       Impact factor: 4.530
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.