| Literature DB >> 14643309 |
Charles W Lugar1, David Magee, Mary D Adrian, Pamela Shetler, Henry U Bryant, Jeffrey A Dodge.
Abstract
The pharmacology and SAR of representative equine estogens is described. 17alpha-Dihydroequilenin was found to prevent bone loss after 5 weeks of oral administration to ovariectomized rats. The stereochemical significance of the D-ring and the C/D ring juncture was investigated with a series of benzothiophene-based equilenin analogues.Entities:
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Year: 2003 PMID： 14643309 DOI： 10.1016/j.bmcl.2003.09.060
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823