Literature DB >> 14643108

Transgenic animals in biomedicine and agriculture: outlook for the future.

M B Wheeler1, E M Walters, S G Clark.   

Abstract

Transgenic animals are produced by introduction of 'foreign' deoxyribonucleic acid (DNA) into preimplantation embryos. The foreign DNA is inserted into the genetic material and may be expressed in tissues of the resulting individual. This technique is of great importance to many aspects of biomedical science including gene regulation, the immune system, cancer research, developmental biology, biomedicine, manufacturing and agriculture. The production of transgenic animals is one of a number of new and developing technologies that will have a profound impact on the genetic improvement of livestock. The rate at which these technologies are incorporated into production schemes will determine the speed at which we will be able to achieve our goal of more efficiently producing livestock, which meets consumer and market demand.

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Year:  2003        PMID: 14643108     DOI: 10.1016/s0378-4320(03)00168-4

Source DB:  PubMed          Journal:  Anim Reprod Sci        ISSN: 0378-4320            Impact factor:   2.145


  11 in total

1.  The creation of transgenic pigs expressing human proteins using BAC-derived, full-length genes and intracytoplasmic sperm injection-mediated gene transfer.

Authors:  Masahito Watanabe; Mayuko Kurome; Hitomi Matsunari; Kazuaki Nakano; Kazuhiro Umeyema; Akira Shiota; Hiromitsu Nakauchi; Hiroshi Nagashima
Journal:  Transgenic Res       Date:  2011-10-25       Impact factor: 2.788

2.  The incredible, edible, and therapeutic egg.

Authors:  James N Petitte; Paul E Mozdziak
Journal:  Proc Natl Acad Sci U S A       Date:  2007-02-01       Impact factor: 11.205

3.  Protein profile and alpha-lactalbumin concentration in the milk of standard and transgenic goats expressing recombinant human butyrylcholinesterase.

Authors:  H Baldassarre; M Schirm; J Deslauriers; C Turcotte; V Bordignon
Journal:  Transgenic Res       Date:  2009-03-19       Impact factor: 2.788

Review 4.  Use of intracytoplasmic sperm injection (ICSI) to generate transgenic animals.

Authors:  Stefan Moisyadi; Joseph M Kaminski; Ryuzo Yanagimachi
Journal:  Comp Immunol Microbiol Infect Dis       Date:  2008-08-08       Impact factor: 2.268

5.  Detection of endoplasmic reticulum stress markers and production enhancement treatments in transgenic goats expressing recombinant human butyrylcholinesterase.

Authors:  H Baldassarre; J Deslauriers; N Neveu; V Bordignon
Journal:  Transgenic Res       Date:  2011-02-22       Impact factor: 2.788

6.  Lactation performance of transgenic goats expressing recombinant human butyryl-cholinesterase in the milk.

Authors:  Hernan Baldassarre; Duncan K Hockley; Monique Doré; Eric Brochu; Bernard Hakier; Xin Zhao; Vilceu Bordignon
Journal:  Transgenic Res       Date:  2007-09-13       Impact factor: 2.788

7.  Milk composition studies in transgenic goats expressing recombinant human butyrylcholinesterase in the mammary gland.

Authors:  Hernan Baldassarre; Duncan K Hockley; Benjamen Olaniyan; Eric Brochu; Xin Zhao; Arif Mustafa; Vilceu Bordignon
Journal:  Transgenic Res       Date:  2008-05-16       Impact factor: 2.788

8.  Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline.

Authors:  Kevin R Smith
Journal:  Int J Med Sci       Date:  2004-06-01       Impact factor: 3.738

9.  Comparative proteomics of milk fat globule membrane proteins from transgenic cloned cattle.

Authors:  Shunchao Sui; Jie Zhao; Jianwu Wang; Ran Zhang; Chengdong Guo; Tian Yu; Ning Li
Journal:  PLoS One       Date:  2014-08-18       Impact factor: 3.240

10.  Swine models, genomic tools and services to enhance our understanding of human health and diseases.

Authors:  Eric M Walters; Kevin D Wells; Elizabeth C Bryda; Susan Schommer; Randall S Prather
Journal:  Lab Anim (NY)       Date:  2017-03-22       Impact factor: 12.625

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