Literature DB >> 14643032

Increased serum levels of interleukin-6 in malnourished patients with colorectal cancer.

Tohru Nakagoe1, Takashi Tsuji, Terumitsu Sawai, Kenji Tanaka, Shigekazu Hidaka, Shin ichi Shibasaki, Atsushi Nanashima, Masayuki Ohbatake, Hiroyuki Yamaguchi, Toru Yasutake, Kazuyuki Sugawara, Naoko Inokuchi, Shimeru Kamihira.   

Abstract

Peri-operative serum levels of interleukin-6 (IL-6) were determined in 62 patients who underwent resection of colorectal cancer to clarify the relationship between nutritional status and IL-6 response. Patients were divided into two groups based on creatinine height index: malnourished group (n=13) and normally nourished group (n=49). The preoperative median serum level of IL-6 in the malnourished group was significantly higher than in the normally nourished group (P=0.041). The postoperative median serum level of IL-6 in the malnourished group also tended to be higher. In conclusion, the peri-operative IL-6 response may be activated in malnourished colorectal cancer patients.

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Year:  2003        PMID: 14643032     DOI: 10.1016/j.canlet.2003.09.008

Source DB:  PubMed          Journal:  Cancer Lett        ISSN: 0304-3835            Impact factor:   8.679


  2 in total

1.  Health behaviors predict higher interleukin-6 levels among patients newly diagnosed with head and neck squamous cell carcinoma.

Authors:  Sonia A Duffy; Theodoros Teknos; Jeremy M G Taylor; Karen E Fowler; Mozaffarul Islam; Gregory T Wolf; Scott McLean; Tamer A Ghanem; Jeffrey E Terrell
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2013-01-08       Impact factor: 4.254

2.  The -174 G/C polymorphism in interleukin-6 (IL-6) promoter region is associated with serum IL-6 and carcinoembryonic antigen levels in patients with colorectal cancers in Taiwan.

Authors:  Kun-Yun Yeh; Ying-Ying Li; Ling-Ling Hsieh; Jim-Ray Chen; Rei-Ping Tang
Journal:  J Clin Immunol       Date:  2009-08-29       Impact factor: 8.317

  2 in total

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