| Literature DB >> 14642851 |
M Devrim Dogan1, Vladimir A Kulchitsky, Shreya Patel, Erika Pétervári, Miklós Székely, Andrej A Romanovsky.
Abstract
Intraperitoneal capsaicin desensitizes sensory fibers traveling within both the vagus and splanchnic nerves. Because capsaicin desensitization blocks the first phase of lipopolysaccharide (LPS) fever, whereas surgical vagotomy does not, splanchnic mediation of the first phase was proposed. However, all phases of the febrile response of splanchnicotomized rats to intravenous LPS (10 microg/kg) were similar to those of sham-operated controls. Hence, the splanchnic nerve is likely uninvolved in LPS fever.Entities:
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Year: 2003 PMID： 14642851 DOI： 10.1016/j.brainres.2003.09.010
Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252