Literature DB >> 14642579

Quantitative structure-activity relationship study on sulfanilamide schiff's bases: carbonic anhydrase (CA) inhibitors.

Vijay K Agrawal1, Shachi Srivastava, Padmakar V Khadikar, Claudiu T Supuran.   

Abstract

The paper deals with quantitative structure-activity studies on a group of sulfanilamide Schiff's base inhibitors of carbonic anhydrase (CA) using distance-based topological indices. The regression analysis of the data has shown that the activities of the compounds used in inhibiting Carbonic AnhydraseII (CAII) activity can be modeled excellently in multi-parametric model in that some indicator parameters are also involved. The results are discussed critically.

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Year:  2003        PMID: 14642579     DOI: 10.1016/j.bmc.2003.09.037

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  1 in total

1.  Some QSAR studies for a group of sulfonamide Schiff base as carbonic anhydrase CA II inhibitors.

Authors:  Erol Eroglu
Journal:  Int J Mol Sci       Date:  2008-02-26       Impact factor: 6.208

  1 in total

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