| Literature DB >> 14640762 |
J W Tunnell1, A E Desjardins, L Galindo, I Georgakoudi, S A McGee, J Mirkovic, M G Mueller, J Nazemi, F T Nguyen, A Wax, Q Zhang, R R Dasari, M S Feld.
Abstract
Reflectance and fluorescence spectroscopies have shown great promise for early detection of epithelial dysplasia. We have developed a clinical reflectance spectrofluorimeter for multimodal spectroscopic diagnosis of epithelial dysplasia. This clinical instrument, the FastEEM, collects white light reflectance and fluorescence excitation-emission matrices (EEM's) within a fraction of a second. In this paper we describe the FastEEM instrumentation, designed for collection of multi-modal spectroscopic data. We illustrate its performance using tissue phantoms with well defined optical properties and biochemicals of known fluorescence properties. In addition, we discuss our plans to develop a system that combines a multi-spectral imaging device for wide area surveillance with this contact probe device.Entities:
Mesh：
Year: 2003 PMID： 14640762 DOI： 10.1177/153303460300200603
Source DB: PubMed Journal: Technol Cancer Res Treat ISSN： 1533-0338