Literature DB >> 14640036

Cellular consequences of transthyretin deposition.

Maria J Saraiva1.   

Abstract

Mutant forms of transthyretin (TTR) deposit in tissues of patients presenting with familial amyloidotic polyneuropathy (FAP). The cellular consequences of tissue TTR deposition have only been addressed recently and are summarized here. Inflammatory and oxidative stress pathways are triggered by fibrillar and non-fibrillar TTR deposits, a fact to take into account in future forms of FAP treatment.

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Year:  2003        PMID： 14640036

Source DB:  PubMed          Journal:  Amyloid        ISSN： 1350-6129            Impact factor:   7.141


  8 in total

1.  A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.

Authors:  Sungwook Choi; Natàlia Reixach; Stephen Connelly; Steven M Johnson; Ian A Wilson; Jeffery W Kelly
Journal:  J Am Chem Soc       Date:  2010-02-03       Impact factor: 15.419

2.  Transthyretin is up-regulated by sex hormones in mice liver.

Authors:  I Gonçalves; C H Alves; T Quintela; G Baltazar; S Socorro; M J Saraiva; R Abreu; C R A Santos
Journal:  Mol Cell Biochem       Date:  2008-06-22       Impact factor: 3.396

3.  Human placental transthyretin in fetal growth restriction in combination with preeclampsia and the HELLP syndrome.

Authors:  Arrigo Fruscalzo; R Schmitz; W Klockenbusch; G Köhler; A P Londero; M Siwetz; B Huppertz
Journal:  Histochem Cell Biol       Date:  2012-07-31       Impact factor: 4.304

4.  Amyloidogenic and associated proteins in systemic amyloidosis proteome of adipose tissue.

Authors:  Francesca Lavatelli; David H Perlman; Brian Spencer; Tatiana Prokaeva; Mark E McComb; Roger Théberge; Lawreen H Connors; Vittorio Bellotti; David C Seldin; Giampaolo Merlini; Martha Skinner; Catherine E Costello
Journal:  Mol Cell Proteomics       Date:  2008-05-12       Impact factor: 5.911

5.  A density-based proteomics sample fractionation technology: folate deficiency induced oxidative stress response in liver and brain.

Authors:  Wenkui Lan; Jayita Guhaniyogi; Marc J Horn; Jun Q Xia; Beverly Graham
Journal:  J Biomol Tech       Date:  2007-09

6.  Late-onset familial amyloid polyneuropathy (FAP) Val30Met without family history.

Authors:  Thomas Rudolph; Martin Wilhelm Kurz; Elisabeth Farbu
Journal:  Clin Med Res       Date:  2008-07-07

7.  THAOS: gastrointestinal manifestations of transthyretin amyloidosis - common complications of a rare disease.

Authors:  Jonas Wixner; Rajiv Mundayat; Onur N Karayal; Intissar Anan; Pontus Karling; Ole B Suhr
Journal:  Orphanet J Rare Dis       Date:  2014-04-27       Impact factor: 4.123

8.  Genotype-phenotype correlation and course of transthyretin familial amyloid polyneuropathies in France.

Authors:  Louise-Laure Mariani; Pierre Lozeron; Marie Théaudin; Zoia Mincheva; Aissatou Signate; Beatrice Ducot; Vincent Algalarrondo; Christian Denier; Clovis Adam; Guillaume Nicolas; Didier Samuel; Michel S Slama; Catherine Lacroix; Micheline Misrahi; David Adams
Journal:  Ann Neurol       Date:  2015-10-07       Impact factor: 10.422
  8 in total

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