Literature DB >> 14639440

A cluster of nosocomial Klebsiella pneumoniae bloodstream infections in a neonatal intensive care department: Identification of transmission and intervention.

Petra Gastmeier1, Katrin Groneberg, Klaus Weist, Henning Rüden.   

Abstract

OBJECTIVE: We sought to determine the cause and mode of transmission of a cluster of bloodstream infections as a result of Klebsiella pneumoniae. DESIGN AND
SETTING: We conducted a prospective cohort study in a neonatal intensive care department from May 1999 to December 2000.
METHODS: We performed surveillance of nosocomial infections, and clinical and environmental investigations.
RESULTS: During an 8-week period, 5 cases of K pneumoniae bloodstream infections were observed, at least 3 of them belonging to the same genotype. Before the second case developed any symptoms of infection, the same strain had also been found in the patient environment. Intervention measures were, therefore, immediately introduced. Further cases, however, occurred in the following weeks. Even after further intervention activities and the end of the outbreak, the same strain was discovered in environmental samples from a stethoscope and a nurse's hand.
CONCLUSIONS: Even where there is acute awareness of the problem and a generally high infection control level in a department, it is difficult to change behavior in such a way that further nosocomial infections can be totally excluded.

Entities:  

Mesh:

Year:  2003        PMID: 14639440     DOI: 10.1067/mic.2003.70

Source DB:  PubMed          Journal:  Am J Infect Control        ISSN: 0196-6553            Impact factor:   2.918


  11 in total

1.  Gastrointestinal colonization with ESBL-producing Klebsiella in preterm babies--is vancomycin to blame?

Authors:  N Ofek-Shlomai; S Benenson; Z Ergaz; O Peleg; R Braunstein; B Bar-Oz
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2011-08-04       Impact factor: 3.267

2.  Colonization and resistance dynamics of gram-negative bacteria in patients during and after hospitalization.

Authors:  P Margreet G Filius; Inge C Gyssens; Irma M Kershof; Patty J E Roovers; Alewijn Ott; Arnold G Vulto; Henri A Verbrugh; Hubert P Endtz
Journal:  Antimicrob Agents Chemother       Date:  2005-07       Impact factor: 5.191

3.  Genome sequencing and comparative analysis of Klebsiella pneumoniae NTUH-K2044, a strain causing liver abscess and meningitis.

Authors:  Keh-Ming Wu; Ling-Hui Li; Jing-Jou Yan; Nina Tsao; Tsai-Lien Liao; Hui-Chi Tsai; Chang-Phone Fung; Hsiang-Ju Chen; Yen-Ming Liu; Jin-Tung Wang; Chi-Tai Fang; Shan-Chwen Chang; Hung-Yu Shu; Tze-Tze Liu; Ying-Tsong Chen; Yih-Ru Shiau; Tsai-Ling Lauderdale; Ih-Jen Su; Ralph Kirby; Shih-Feng Tsai
Journal:  J Bacteriol       Date:  2009-05-15       Impact factor: 3.490

4.  Etiology of neonatal blood stream infections in Tbilisi, Republic of Georgia.

Authors:  Nino Macharashvili; Ekaterina Kourbatova; Maia Butsashvili; Tengiz Tsertsvadze; Louise-Anne McNutt; Michael K Leonard
Journal:  Int J Infect Dis       Date:  2008-12-05       Impact factor: 3.623

5.  Bacteriological assessment of stethoscopes used by healthcare workers in a tertiary care centre of Nepal.

Authors:  Sangita Thapa; Lokendra Bahadur Sapkota
Journal:  BMC Res Notes       Date:  2017-07-28

6.  The Washing Machine as a Reservoir for Transmission of Extended-Spectrum-Beta-Lactamase (CTX-M-15)-Producing Klebsiella oxytoca ST201 to Newborns.

Authors:  Ricarda M Schmithausen; Esther Sib; Martin Exner; Sylvia Hack; Claudia Rösing; Patrick Ciorba; Gabriele Bierbaum; Mykhailo Savin; Sally F Bloomfield; Martin Kaase; Anja Jacobshagen; Stefanie Gemein; Jürgen Gebel; Steffen Engelhart; Daniel Exner
Journal:  Appl Environ Microbiol       Date:  2019-10-30       Impact factor: 4.792

7.  The emergence of multidrug-resistant Klebsiella pneumoniae of international clones ST13, ST16, ST35, ST48 and ST101 in a teaching hospital in the Paris region.

Authors:  G Marcade; S Brisse; S Bialek; E Marcon; V Leflon-Guibout; V Passet; R Moreau; M-H Nicolas-Chanoine
Journal:  Epidemiol Infect       Date:  2012-10-04       Impact factor: 4.434

8.  Outbreak of ampicillin/piperacillin-resistant Klebsiella pneumoniae in a neonatal intensive care unit (NICU): investigation and control measures.

Authors:  Giuliana Fabbri; Manuela Panico; Laura Dallolio; Roberta Suzzi; Matilde Ciccia; Fabrizio Sandri; Patrizia Farruggia
Journal:  Int J Environ Res Public Health       Date:  2013-02-26       Impact factor: 3.390

9.  Time Effectiveness of Ultraviolet C Light (UVC) Emitted by Light Emitting Diodes (LEDs) in Reducing Stethoscope Contamination.

Authors:  Gabriele Messina; Mattia Fattorini; Nicola Nante; Daniele Rosadini; Andrea Serafini; Marco Tani; Gabriele Cevenini
Journal:  Int J Environ Res Public Health       Date:  2016-09-23       Impact factor: 3.390

Review 10.  Spatial and temporal analyses to investigate infectious disease transmission within healthcare settings.

Authors:  G S Davis; N Sevdalis; L N Drumright
Journal:  J Hosp Infect       Date:  2014-02-26       Impact factor: 3.926

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