Literature DB >> 1463873

Expression of the pS2 gene in breast tissues assessed by pS2-mRNA analysis and pS2-protein radioimmunoassay.

E Hähnel1, P Robbins, J Harvey, G Sterrett, R Hähnel.   

Abstract

The expression of the pS2 gene in breast tissues was assessed by measuring pS2-protein using a radioimmunoassay, and by determining pS2-mRNA using Northern blotting. There was a good correlation between the two measurements, indicating that expression of the pS2 gene in breast tissues may be assessed by either method. Since radioimmunoassay is technically easier and more efficient than Northern blotting, radioimmunoassay will be the method of choice in routine applications.

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Year:  1992        PMID： 1463873     DOI： 10.1007/bf01832360

Source DB:  PubMed          Journal:  Breast Cancer Res Treat        ISSN： 0167-6806            Impact factor:   4.872


  7 in total

1.  Detection of estradiol-induced messenger RNA (pS2) in uninvolved breast tissue from mastectomies for breast cancer.

Authors:  E Hähnel; R Joyce; G Sterrett; J Harvey; R Hähnel
Journal:  Breast Cancer Res Treat       Date:  1992-03       Impact factor: 4.872

2.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

Authors:  M M Bradford
Journal:  Anal Biochem       Date:  1976-05-07       Impact factor: 3.365

3.  Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line.

Authors:  P Masiakowski; R Breathnach; J Bloch; F Gannon; A Krust; P Chambon
Journal:  Nucleic Acids Res       Date:  1982-12-20       Impact factor: 16.971

4.  Specific expression of the pS2 gene in subclasses of breast cancers in comparison with expression of the estrogen and progesterone receptors and the oncogene ERBB2.

Authors:  M C Rio; J P Bellocq; B Gairard; U B Rasmussen; A Krust; C Koehl; H Calderoli; V Schiff; R Renaud; P Chambon
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

5.  Prognostic value of pS2 protein and receptors for epidermal growth factor (EGF-R), insulin-like growth factor-1 (IGF-1-R) and somatostatin (SS-R) in patients with breast and ovarian cancer.

Authors:  J A Foekens; W L van Putten; H Portengen; C J Rodenburg; J C Reubi; P M Berns; S C Henzen-Logmans; M E van der Burg; J Alexieva-Figusch; J G Klijn
Journal:  J Steroid Biochem Mol Biol       Date:  1990-12-20       Impact factor: 4.292

6.  Prediction of relapse and survival in breast cancer patients by pS2 protein status.

Authors:  J A Foekens; M C Rio; P Seguin; W L van Putten; J Fauque; M Nap; J G Klijn; P Chambon
Journal:  Cancer Res       Date:  1990-07-01       Impact factor: 12.701

7.  pNR-2/pS2 immunohistochemical staining in breast cancer: correlation with prognostic factors and endocrine response.

Authors:  J A Henry; N H Piggott; U K Mallick; S Nicholson; J R Farndon; B R Westley; F E May
Journal:  Br J Cancer       Date:  1991-04       Impact factor: 7.640
  7 in total
  2 in total

1.  Expression of the pS2 gene in normal breast tissue.

Authors:  E Hähnel; P Robbins; R Hähnel
Journal:  Breast Cancer Res Treat       Date:  1993-12       Impact factor: 4.872

2.  Immunohistochemical and biochemical analysis of the oestrogen regulated protein pS2, and its relation with oestrogen receptor and progesterone receptor in breast cancer.

Authors:  S Detre; N King; J Salter; K MacLennan; J A McKinna; M Dowsett
Journal:  J Clin Pathol       Date:  1994-03       Impact factor: 3.411
  2 in total

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