Literature DB >> 14636550

Embryonic stem cell self-renewal, analyzed.

Sally Temple1.   

Abstract

Maintaining the pluripotency of mouse ES cells requires both LIF (leukemia inhibitory factor) and unknown factors in serum. The paper from Ying et al. in this issue of Cell shows that BMP (bone morphogenetic protein) can replace serum in this capacity, defining molecular requirements for ES cell self-renewal.

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Year:  2003        PMID: 14636550     DOI: 10.1016/s0092-8674(03)00853-5

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  1 in total

1.  Cdk2ap1 is required for epigenetic silencing of Oct4 during murine embryonic stem cell differentiation.

Authors:  Amit M Deshpande; Yan-Shan Dai; Yong Kim; Jeffrey Kim; Lauren Kimlin; Kai Gao; David T Wong
Journal:  J Biol Chem       Date:  2008-12-31       Impact factor: 5.157

  1 in total

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