| Literature DB >> 14636550 |
Abstract
Maintaining the pluripotency of mouse ES cells requires both LIF (leukemia inhibitory factor) and unknown factors in serum. The paper from Ying et al. in this issue of Cell shows that BMP (bone morphogenetic protein) can replace serum in this capacity, defining molecular requirements for ES cell self-renewal.Entities:
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Year: 2003 PMID: 14636550 DOI: 10.1016/s0092-8674(03)00853-5
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582