| Literature DB >> 1463583 |
Abstract
This new view of the immunoreactivity of the normal brain is based on three key components. First, there is an active and highly-regulated communication between the brain and the central immune organs. Secondly, the connection from the brain to the draining nodes is much larger than previously appreciated. And third, the blood-brain barrier, by virtue of its selective permeability properties, contributes to the regulation of immunoregulatory cells and molecules in the brain cell microenvironment.Mesh:
Substances:
Year: 1992 PMID: 1463583 DOI: 10.1016/0167-5699(92)90027-5
Source DB: PubMed Journal: Immunol Today ISSN: 0167-5699