Literature DB >> 1463582

GM-CSF, IL-3 and IL-5: cross-competition on human haemopoietic cells.

A F Lopez1, M J Elliott, J Woodcock, M A Vadas.   

Abstract

The biological properties of GM-CSF, IL-3 and IL-5 are multiple; initially described as haemopoietic growth factors, they also regulate inflammation, allergic reactions and cell adherence. The receptors for these three cytokines share a common component which may play a key role in their biological activity. This review describes the potential roles of GM-CSF, IL-3 and IL-5 in inflammation and discusses approaches to modulate their function.

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Year:  1992        PMID： 1463582     DOI： 10.1016/0167-5699(92)90025-3

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  28 in total

1.  Cytokines induce selective granulocyte chemotactic responses.

Authors:  D B Bittleman; R A Erger; T B Casale
Journal:  Inflamm Res       Date:  1996-02       Impact factor: 4.575

2.  Lymphocytes stimulate expression of 5-lipoxygenase and its activating protein in monocytes in vitro via granulocyte macrophage colony-stimulating factor and interleukin 3.

Authors:  W L Ring; C A Riddick; J R Baker; D A Munafo; T D Bigby
Journal:  J Clin Invest       Date:  1996-03-01       Impact factor: 14.808

Review 3.  Pathogenesis and classification of eosinophil disorders: a review of recent developments in the field.

Authors:  Peter Valent; Gerald J Gleich; Andreas Reiter; Florence Roufosse; Peter F Weller; Andrzej Hellmann; Georgia Metzgeroth; Kristin M Leiferman; Michel Arock; Karl Sotlar; Joseph H Butterfield; Sabine Cerny-Reiterer; Matthias Mayerhofer; Peter Vandenberghe; Torsten Haferlach; Bruce S Bochner; Jason Gotlib; Hans-Peter Horny; Hans-Uwe Simon; Amy D Klion
Journal:  Expert Rev Hematol       Date:  2012-04       Impact factor: 2.929

4.  Monomeric isomers of human interleukin 5 show that 1:1 receptor recruitment is sufficient for function.

Authors:  J Li; R Cook; M L Doyle; P Hensley; D E McNulty; I Chaiken
Journal:  Proc Natl Acad Sci U S A       Date:  1997-06-24       Impact factor: 11.205

Review 5.  Therapeutic approaches to asthma based on VLA-4 integrin and its counter receptors.

Authors:  W J Metzger
Journal:  Springer Semin Immunopathol       Date:  1995

Review 6.  The eosinophil leukocyte: controversies of recruitment and function.

Authors:  L P Bignold
Journal:  Experientia       Date:  1995-04-15

7.  Mutagenesis in the C-terminal region of human interleukin 5 reveals a central patch for receptor alpha chain recognition.

Authors:  T Morton; J Li; R Cook; I Chaiken
Journal:  Proc Natl Acad Sci U S A       Date:  1995-11-21       Impact factor: 11.205

8.  Human interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but not high-affinity binding.

Authors:  F C Stomski; Q Sun; C J Bagley; J Woodcock; G Goodall; R K Andrews; M C Berndt; A F Lopez
Journal:  Mol Cell Biol       Date:  1996-06       Impact factor: 4.272

9.  Allergen-induced increases in IL-5 receptor alpha-subunit expression on bone marrow-derived CD34+ cells from asthmatic subjects. A novel marker of progenitor cell commitment towards eosinophilic differentiation.

Authors:  R Sehmi; L J Wood; R Watson; R Foley; Q Hamid; P M O'Byrne; J A Denburg
Journal:  J Clin Invest       Date:  1997-11-15       Impact factor: 14.808

10.  The receptor for interleukin 3 is selectively induced in human endothelial cells by tumor necrosis factor alpha and potentiates interleukin 8 secretion and neutrophil transmigration.

Authors:  E I Korpelainen; J R Gamble; W B Smith; G J Goodall; S Qiyu; J M Woodcock; M Dottore; M A Vadas; A F Lopez
Journal:  Proc Natl Acad Sci U S A       Date:  1993-12-01       Impact factor: 11.205
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