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Literature DB >> 146337

Phagocytosis of monocytes in cancer patients.

Abstract

The phagocytic activity of monocytes directed at yeast particles was investigated in patients with untreated malignant tumors and in normal controls. Phagocytic activity was found to be significantly increased in the patients. It could be shown that the increased activity is caused by factors contained in the patient's plasma. These factors are only partly destroyed by heat inactivation, suggesting that both heat labile and heat stabile factors are contributing to the observed enhancing effect on phagocytic activity. The heat labile portion could well be the complement component C5, while the heat stabile portion is so far undefined.

Entities: Disease Species

Mesh：

Year: 1978 PMID： 146337 DOI： 10.1007/bf00305967

Source DB: PubMed Journal: Z Krebsforsch Klin Onkol Cancer Res Clin Oncol ISSN： 0084-5353

14 in total

1. The role of the reticuloendothelial system in the host reaction to neoplasia.

Authors: L J OLD; B BENACERRAF; D A CLARKE; E A CARSWELL; E STOCKERT
Journal: Cancer Res Date: 1961-10 Impact factor: 12.701

2. Abnormal monocyte chemotactic response in cancer patients.

Authors: D A Boetcher; E J Leonard
Journal: J Natl Cancer Inst Date: 1974-04 Impact factor: 13.506

3. Current methods for the cryopreservation of human leukocytes (granulocytes).

Authors: J A Cavins; I Djerassi; E Aghai; A J Roy
Journal: Cryobiology Date: 1968 Jul-Aug Impact factor: 2.487

4. Changes in the opsonin and cellular influences on phagocytosis during the growth of transplantable tumors.

Authors: R F Kampschmidt; L A Pulliam
Journal: J Reticuloendothel Soc Date: 1972-01

5. Reticulo-endothelial activity in humans with cancer.

Authors: C J Magarey; M Baum
Journal: Br J Surg Date: 1970-10 Impact factor: 6.939

6. Cooperation of immune lymphoid cells with macrophages in tumour immunity.

Authors: R Evans; P Alexander
Journal: Nature Date: 1970-11-14 Impact factor: 49.962

7. A major role of the fifth component of complement (C5) in the opsonization of yeast particles. Partial dichotomy of function and immunochemical measurement.

Authors: M E Miller; U R Nilsson
Journal: Clin Immunol Immunopathol Date: 1974-01

Phagocytosis of monocytes in cancer patients.

1. The role of the reticuloendothelial system in the host reaction to neoplasia.

2. Abnormal monocyte chemotactic response in cancer patients.

3. Current methods for the cryopreservation of human leukocytes (granulocytes).

4. Changes in the opsonin and cellular influences on phagocytosis during the growth of transplantable tumors.

5. Reticulo-endothelial activity in humans with cancer.

6. Cooperation of immune lymphoid cells with macrophages in tumour immunity.

7. A major role of the fifth component of complement (C5) in the opsonization of yeast particles. Partial dichotomy of function and immunochemical measurement.

Review 8. Origin and kinetics of monocytes and macrophages.

9. Phagocytic activity of the reticuloendothelial system in neoplastic disease.

10. Immunosuppression and plasma-exchange in the treatment of Goodpasture's syndrome.

Review 1. Disordered function of mononuclear phagocytes in malignant disease.

2. A quantitative and qualitative study of blood monocytes in patients with bronchogenic carcinoma.