| Literature DB >> 14633391 |
Abstract
We prove that it is impossible to reconstruct ancestral data at the root of "deep" phylogenetic trees with high mutation rates. Moreover, we prove that it is impossible to reconstruct the topology of "deep" trees with high mutation rates from a number of characters smaller than a low-degree polynomial in the number of leaves. Our impossibility results hold for all reconstruction methods. The proofs apply tools from information theory and percolation theory.Mesh:
Year: 2003 PMID: 14633391 DOI: 10.1089/106652703322539015
Source DB: PubMed Journal: J Comput Biol ISSN: 1066-5277 Impact factor: 1.479