Literature DB >> 14631056

Hospitalization in the first year of renal replacement therapy for end-stage renal disease.

W Metcalfe1, I H Khan, G J Prescott, K Simpson, A M Macleod.   

Abstract

BACKGROUND: The requirement for hospitalization of patients on dialysis is likely to be a surrogate marker of age and comorbid diseases. It may also reflect the level of care delivered, and substantially increases the cost of this expensive therapy. AIM: To identify the factors most strongly associated with hospitalization.
DESIGN: Prospective population study.
METHODS: Data were recorded for all patients starting RRT in Scotland over one year, including the reasons for and duration of, each hospital admission during the first year of RRT. Factors most strongly associated with hospitalization were determined by Poisson regression analysis.
RESULTS: Overall, 526 patients were admitted to hospital on 1668 occasions (median 3, IQR 1-4) for 13384 days (median 13, IQR 4-35). Formation of vascular access for haemodialysis (HD) was the most frequent reason for admission, followed by infections. Age, comorbidity, mode of presentation for RRT and primary renal diagnosis were all significantly associated with prolonged hospitalization. Attainment of UK Renal Association standards for urea reduction ratio and serum albumin concentration, and vascular access in the form of arterio-venous fistulae were associated with less hospitalization in patients treated with HD by 90 days. DISCUSSION: Patients in their first year of RRT have a high requirement for in-patient care, 8.6% of patient treatment days being spent in hospital. Vascular access formation, failure and complications account for a large proportion of this. Age and comorbidity prolong the time spent in hospital. As the RRT population continues to increase, with older patients and those with greater comorbidity, in-patient facilities must also expand.

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Year:  2003        PMID: 14631056     DOI: 10.1093/qjmed/hcg155

Source DB:  PubMed          Journal:  QJM        ISSN: 1460-2393


  13 in total

1.  Trajectories of kidney function decline in the 2 years before initiation of long-term dialysis.

Authors:  Ann M O'Hare; Adam Batten; Nilka Ríos Burrows; Meda E Pavkov; Leslie Taylor; Indra Gupta; Jeff Todd-Stenberg; Charles Maynard; Rudolph A Rodriguez; Fliss E M Murtagh; Eric B Larson; Desmond E Williams
Journal:  Am J Kidney Dis       Date:  2012-02-04       Impact factor: 8.860

Review 2.  Reducing hospital readmissions in patients with end-stage kidney disease.

Authors:  Anna T Mathew; Giovanni F M Strippoli; Marinella Ruospo; Steven Fishbane
Journal:  Kidney Int       Date:  2015-10-14       Impact factor: 10.612

3.  Effects of Losartan-based therapy on the incidence of end-stage renal disease and associated costs in type 2 diabetes mellitus: A retrospective cost-effectiveness analysis in the United Kingdom.

Authors:  Jiten Vora; George Carides; Paul Robinson
Journal:  Curr Ther Res Clin Exp       Date:  2005-11

4.  Change in vascular access and hospitalization risk in long-term hemodialysis patients.

Authors:  Eduardo Lacson; Weiling Wang; J Michael Lazarus; Raymond M Hakim
Journal:  Clin J Am Soc Nephrol       Date:  2010-09-30       Impact factor: 8.237

5.  Clinical outcome of home hemodialysis in patients with previous peritoneal dialysis exposure: evaluation of the integrated home dialysis model.

Authors:  Annie-Claire Nadeau-Fredette; Joanne M Bargman; Christopher T Chan
Journal:  Perit Dial Int       Date:  2014-03-01       Impact factor: 1.756

6.  Association of initial hemodialysis vascular access with patient-reported health status and quality of life.

Authors:  Haimanot Wasse; Nancy Kutner; Rebecca Zhang; Yijian Huang
Journal:  Clin J Am Soc Nephrol       Date:  2007-05-18       Impact factor: 8.237

7.  Health Insurance in the First 3 Months of Hemodialysis and Early Vascular Access.

Authors:  Eugene Lin; Matthew W Mell; Wolfgang C Winkelmayer; Kevin F Erickson
Journal:  Clin J Am Soc Nephrol       Date:  2018-11-01       Impact factor: 8.237

8.  Predicting hospital costs for patients receiving renal replacement therapy to inform an economic evaluation.

Authors:  Bernadette Li; John Cairns; James Fotheringham; Rommel Ravanan
Journal:  Eur J Health Econ       Date:  2015-07-08

9.  Modifiable risk factors for early mortality on hemodialysis.

Authors:  Rory McQuillan; Lilyanna Trpeski; Stanley Fenton; Charmaine E Lok
Journal:  Int J Nephrol       Date:  2012-07-24

Review 10.  Reimbursement and economic factors influencing dialysis modality choice around the world.

Authors:  Paul M Just; Frank Th de Charro; Elizabeth A Tschosik; Les L Noe; Samir K Bhattacharyya; Miguel C Riella
Journal:  Nephrol Dial Transplant       Date:  2008-01-30       Impact factor: 5.992

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