Literature DB >> 14630221

Systems biology in neuroscience: bridging genes to cognition.

Seth G N Grant1.   

Abstract

Systems biology is a new branch of biology aimed at understanding biological complexity. Genomic and proteomic methods integrated with cellular and organismal analyses allow modelling of physiological processes. Progress in understanding synapse composition and new experimental and bioinformatics methods indicate the synapse is an excellent starting point for global systems biology of the brain. A neuroscience systems biology programme, organized as a consortium, is proposed.

Mesh：

Year:  2003        PMID： 14630221     DOI： 10.1016/j.conb.2003.09.016

Source DB:  PubMed          Journal:  Curr Opin Neurobiol        ISSN： 0959-4388            Impact factor:   6.627


  11 in total

1.  High-content microscopy identifies new neurite outgrowth regulators.

Authors:  Vibor Laketa; Jeremy C Simpson; Stephanie Bechtel; Stefan Wiemann; Rainer Pepperkok
Journal:  Mol Biol Cell       Date:  2006-11-08       Impact factor: 4.138

Review 2.  Synaptosome proteomics.

Authors:  Fengju Bai; Frank A Witzmann
Journal:  Subcell Biochem       Date:  2007

Review 3.  On the making of a system theory of life: Paul A Weiss and Ludwig von Bertalanffy's conceptual connection.

Authors:  Manfred Drack; Wilfried Apfalter; David Pouvreau
Journal:  Q Rev Biol       Date:  2007-12       Impact factor: 4.875

Review 4.  Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders.

Authors:  Neelroop N Parikshak; Michael J Gandal; Daniel H Geschwind
Journal:  Nat Rev Genet       Date:  2015-07-07       Impact factor: 53.242

5.  Protein biomarkers for traumatic and ischemic brain injury: from bench to bedside.

Authors:  Zhiqun Zhang; Stefania Mondello; Firas Kobeissy; Richard Rubenstein; Jackson Streeter; Ronald L Hayes; Kevin K W Wang
Journal:  Transl Stroke Res       Date:  2011-12-07       Impact factor: 6.829

6.  Lists2Networks: integrated analysis of gene/protein lists.

Authors:  Alexander Lachmann; Avi Ma'ayan
Journal:  BMC Bioinformatics       Date:  2010-02-12       Impact factor: 3.169

7.  Automated design of genomic Southern blot probes.

Authors:  Mike D R Croning; David G Fricker; Noboru H Komiyama; Seth G N Grant
Journal:  BMC Genomics       Date:  2010-01-29       Impact factor: 3.969

Review 8.  The Application of Proteomics to Traumatic Brain and Spinal Cord Injuries.

Authors:  George Anis Sarkis; Manasi D Mangaonkar; Ahmed Moghieb; Brian Lelling; Michael Guertin; Hamad Yadikar; Zhihui Yang; Firas Kobeissy; Kevin K W Wang
Journal:  Curr Neurol Neurosci Rep       Date:  2017-03       Impact factor: 5.081

9.  SynDB: a Synapse protein DataBase based on synapse ontology.

Authors:  Wuxue Zhang; Yong Zhang; Hui Zheng; Chen Zhang; Wei Xiong; John G Olyarchuk; Michael Walker; Weifeng Xu; Min Zhao; Shuqi Zhao; Zhuan Zhou; Liping Wei
Journal:  Nucleic Acids Res       Date:  2006-11-10       Impact factor: 16.971

10.  Genes2Networks: connecting lists of gene symbols using mammalian protein interactions databases.

Authors:  Seth I Berger; Jeremy M Posner; Avi Ma'ayan
Journal:  BMC Bioinformatics       Date:  2007-10-04       Impact factor: 3.169
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