Literature DB >> 14630002

Immunosuppressive flavones and lignans from Bupleurum scorzonerifolium.

Wen-Liang Chang1, Li-Wen Chiu, Jenn-Haung Lai, Hang-Ching Lin.   

Abstract

Two lignans, isochaihulactone and chaihunaphthone, together with eleven known compounds were isolated from the root of Bupleurum scorzonerifolium. Their structures were established on the basis of spectral evidence. In biological testing, eugenin and saikochromone potently inhibited CD28-costimulated activation of human peripheral blood T cells.

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Year:  2003        PMID: 14630002     DOI: 10.1016/j.phytochem.2003.08.002

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  9 in total

1.  Isochaihulactone protects PC12 cell against H(2)O(2) induced oxidative stress and exerts the potent anti-aging effects in D-galactose aging mouse model.

Authors:  Sung-Liang YU; Shih-bin LIN; Yung-luen YU; Min-hui CHIEN; Kuo-jung SU; Ching-Ju LIN; Tzong-der WAY; Giou-Teng YIANG; Chai-Ching LIN; De-Chuan CHAN; Horng-Jyh HARN; Yi-Lin Sophia CHEN
Journal:  Acta Pharmacol Sin       Date:  2010-11-01       Impact factor: 6.150

2.  Crude polysaccharide from an anti-UVB cell clone of Bupleurum scorzonerifolium protect HaCaT cells against UVB-induced oxidative stress.

Authors:  Jinran Dai; Haiyin Ma; Jing Fan; Yuzhong Li; Jianguang Wang; Hongmei Ni; Guangmin Xia; Suiyun Chen
Journal:  Cytotechnology       Date:  2011-09-27       Impact factor: 2.058

3.  Ipso -Type Regiocontrolled Benzannulation for the Synthesis of Uniquely Substituted α-Arylnaphthalenes: Application to the First Total Synthesis of Chaihunaphthone.

Authors:  Kento Moriguchi; Ryosuke Sasaki; Jun-Ichi Morita; Yoshinobu Kamakura; Daisuke Tanaka; Yoo Tanabe
Journal:  ACS Omega       Date:  2021-07-09

4.  A nonimmunosuppressant approach on Asia psoriasis subjects: 5-year followup and 11-year data analysis.

Authors:  Tony Yuqi Tang
Journal:  Dermatol Res Pract       Date:  2012-01-11

Review 5.  Radix Bupleuri: A Review of Traditional Uses, Botany, Phytochemistry, Pharmacology, and Toxicology.

Authors:  Fude Yang; Xiaoxv Dong; Xingbin Yin; Wenping Wang; Longtai You; Jian Ni
Journal:  Biomed Res Int       Date:  2017-05-16       Impact factor: 3.411

Review 6.  Genus Bupleurum: a review of its phytochemistry, pharmacology and modes of action.

Authors:  Mohamed L Ashour; Michael Wink
Journal:  J Pharm Pharmacol       Date:  2010-11-16       Impact factor: 3.765

7.  Design, Synthesis and Structure-Activity Relationships of (±)-Isochaihulactone Derivatives.

Authors:  Yu Zhao; Po-Yen Liu; Kan-Yen Hsieh; Pei-Ling Hsu; Masuo Goto; Susan L Morris-Natschke; Horng-Jyh Harn; Kuo-Hsiung Lee
Journal:  Medchemcomm       Date:  2017-10-12       Impact factor: 3.597

8.  Rutin, a Flavonoid That Is a Main Component of Saussurea involucrata, Attenuates the Senescence Effect in D-Galactose Aging Mouse Model.

Authors:  Ying-Chen Yang; Hsueh-Yi Lin; Kang-Yi Su; Chien-Hsu Chen; Yung-Lung Yu; Chai-Ching Lin; Sung-Liang Yu; Hong-Young Yan; Kuo-Jung Su; Yi-Lin Sophia Chen
Journal:  Evid Based Complement Alternat Med       Date:  2012-08-16       Impact factor: 2.629

Review 9.  Traditional Use, Pharmacology, Toxicology, and Quality Control of Species in Genus Bupleurum L.

Authors:  Ru-Yu Yao; Yuan-Feng Zou; Xing-Fu Chen
Journal:  Chin Herb Med       Date:  2013-11-23
  9 in total

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