Literature DB >> 1462848

Regulation of bradykinin-induced chloride secretion in a human epithelial cell line.

D H Miller1, A W Baird, S Bennet, M Halushka, M Sasaguri, H Schomer, H S Margolius.   

Abstract

The chloride secretory response to bradykinin in T84 cells is regulated. The efflux rate of 125I from these cells can be used to measure this response, and to demonstrate that the sensitivity to bradykinin varies with time in culture. The response in NuT84 cells is greater than that in T84, and can be blocked by the B2 receptor antagonist HOE-140.

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Year:  1992        PMID： 1462848

Source DB:  PubMed          Journal:  Agents Actions Suppl        ISSN： 0379-0363


  2 in total

1.  Effect of icatibant, a bradykinin B2 receptor antagonist, on the development of experimental ulcerative colitis in mice.

Authors:  Y Arai; H Takanashi; H Kitagawa; K J Wirth; I Okayasu
Journal:  Dig Dis Sci       Date:  1999-04       Impact factor: 3.199

2.  Pathogenic Escherichia coli increase Cl- secretion from intestinal epithelia by upregulating galanin-1 receptor expression.

Authors:  G Hecht; J A Marrero; A Danilkovich; K A Matkowskyj; S D Savkovic; A Koutsouris; R V Benya
Journal:  J Clin Invest       Date:  1999-08       Impact factor: 14.808
  2 in total

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