Literature DB >> 14627382

Asymmetric conjugate addition reactions of Meldrum's acid derived acceptors employing chiral phosphoramidite ligands.

Takumi Watanabe1, Thomas F Knöpfel, Erick M Carreira.   

Abstract

[reaction: see text] The enantioselective conjugate addition reaction of Et(2)Zn to Meldrum's acid derived acceptors, mediated by a catalyst formed from Cu(O(2)CCF(3))(2) and a phosphoramidite ligand, is reported. Adducts are obtained in useful yields and up to 94% ee.

Entities:  

Year:  2003        PMID: 14627382     DOI: 10.1021/ol035575q

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  1 in total

1.  Enantioselective intramolecular hydroarylation of alkenes via directed C-H bond activation.

Authors:  Hitoshi Harada; Reema K Thalji; Robert G Bergman; Jonathan A Ellman
Journal:  J Org Chem       Date:  2008-08-06       Impact factor: 4.354

  1 in total

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