Literature DB >> 14624722

Data modeling and data communication in GenomEUtwin.

Jan-Eric Litton1, Juha Muilu, Ann Björklund, Anne Leinonen, Nancy L Pedersen.   

Abstract

Database infrastructure has become a critical component for competitive life sciences research and discovery. The explosion of data requires that the data are properly loaded, accessed, managed, queried, analyzed, and shared with others. The key purpose of the population-based twin cohorts housed at different institutions in Europe is to gather an extremely large quantity of information from their twin populations, and share it. Longitudinal research over a long period of time, hopefully generations, demands completely new methods and systems to handle the gathering of information and storing. These cohorts bring to the fore problems concerning the need for a standardization of research data and a computer and storage strategy. In the following we describe the preliminary strategy being implemented in the Database Core of GenomEUtwin.

Mesh:

Year:  2003        PMID: 14624722     DOI: 10.1375/136905203770326385

Source DB:  PubMed          Journal:  Twin Res        ISSN: 1369-0523


  3 in total

1.  Quality, quantity and harmony: the DataSHaPER approach to integrating data across bioclinical studies.

Authors:  Isabel Fortier; Paul R Burton; Paula J Robson; Vincent Ferretti; Julian Little; Francois L'Heureux; Mylène Deschênes; Bartha M Knoppers; Dany Doiron; Joost C Keers; Pamela Linksted; Jennifer R Harris; Geneviève Lachance; Catherine Boileau; Nancy L Pedersen; Carol M Hamilton; Kristian Hveem; Marilyn J Borugian; Richard P Gallagher; John McLaughlin; Louise Parker; John D Potter; John Gallacher; Rudolf Kaaks; Bette Liu; Tim Sprosen; Anne Vilain; Susan A Atkinson; Andrea Rengifo; Robin Morton; Andres Metspalu; H Erich Wichmann; Mark Tremblay; Rex L Chisholm; Andrés Garcia-Montero; Hans Hillege; Jan-Eric Litton; Lyle J Palmer; Markus Perola; Bruce H R Wolffenbuttel; Leena Peltonen; Thomas J Hudson
Journal:  Int J Epidemiol       Date:  2010-09-02       Impact factor: 7.196

2.  Realizing the promise of population biobanks: a new model for translation.

Authors:  Madeleine J Murtagh; Ipek Demir; Jennifer R Harris; Paul R Burton
Journal:  Hum Genet       Date:  2011-06-25       Impact factor: 4.132

3.  Combined genome scans for body stature in 6,602 European twins: evidence for common Caucasian loci.

Authors:  Markus Perola; Sampo Sammalisto; Tero Hiekkalinna; Nick G Martin; Peter M Visscher; Grant W Montgomery; Beben Benyamin; Jennifer R Harris; Dorret Boomsma; Gonneke Willemsen; Jouke-Jan Hottenga; Kaare Christensen; Kirsten Ohm Kyvik; Thorkild I A Sørensen; Nancy L Pedersen; Patrik K E Magnusson; Tim D Spector; Elisabeth Widen; Karri Silventoinen; Jaakko Kaprio; Aarno Palotie; Leena Peltonen
Journal:  PLoS Genet       Date:  2007-05-02       Impact factor: 5.917

  3 in total

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