| Literature DB >> 14623817 |
Patrick P L Tam1, Janet Rossant.
Abstract
Embryonic chimeras of the mouse are well-established tools for studying cell lineage and cell potential. They are also a key part of the analysis of complex phenotypes of mutant mice. By combining embryonic stem cell technology, molecularly tagged mutations and sensitive cell lineage markers, chimeras can provide invaluable insights into the tissue-specific requirement and the mode of action of many mouse genes.Entities:
Mesh:
Year: 2003 PMID: 14623817 DOI: 10.1242/dev.00893
Source DB: PubMed Journal: Development ISSN: 0950-1991 Impact factor: 6.868