Photodynamic therapy with verteporfin for classic choroidal neovascularization secondary to focal laser photocoagulation for radiation retinopathy.

A 50-year-old patient developed extrafoveal predominantly classic choroidal neovascularization in the right eye 2 months after undergoing focal laser photocoagulation for macular edema with hard exudates secondary to radiation retinopathy, with vision dropping from 20/20 to 20/100. The choroidal neovascularization responded to three verteporfin photodynamic therapy treatments with angiographic closure, which persisted for more than 15 months after the last treatment. At last follow-up 15 months after the third treatment, visual acuity improved by 8 lines to 20/20. Photodynamic therapy with verteporfin may be useful for treating patients with choroidal neovascularization secondary to argon laser photocoagulation.