Literature DB >> 14618930

Numerical simulation of flow in mechanical heart valves: grid resolution and the assumption of flow symmetry.

Liang Ge1, S Casey Jones, Fotis Sotiropoulos, Timothy M Healy, Ajit P Yoganathan.   

Abstract

A numerical method is developed for simulating unsteady, 3-D, laminar flow through a bileaflet mechanical heart valve with the leaflets fixed. The method employs a dual-time-stepping artificial-compressibility approach together with overset (Chimera) grids and is second-order accurate in space and time. Calculations are carried out for the full 3-D valve geometry under steady inflow conditions on meshes with a total number of nodes ranging from 4 x 10(5) to 1.6 x 10(6). The computed results show that downstream of the leaflets the flow is dominated by two pairs of counter-rotating vortices, which originate on either side of the central orifice in the aortic sinus and rotate such that the common flow of each pair is directed away from the aortic wall. These vortices intensify with Reynolds number, and at a Reynolds number of approximately 1200 their complex interaction leads to the onset of unsteady flow and the break of symmetry with respect to both geometric planes of symmetry. Our results show the highly 3-D structure of the flow; question the validity of computationally expedient assumptions of flow symmetry; and demonstrate the need for highly resolved, fully 3-D simulations if computational fluid dynamics is to accurately predict the flow in prosthetic mechanical heart valves.

Mesh:

Year:  2003        PMID: 14618930     DOI: 10.1115/1.1614817

Source DB:  PubMed          Journal:  J Biomech Eng        ISSN: 0148-0731            Impact factor:   2.097


  16 in total

1.  Measurements of steady flow through a bileaflet mechanical heart valve using stereoscopic PIV.

Authors:  Chris Hutchison; Pierre Sullivan; C Ross Ethier
Journal:  Med Biol Eng Comput       Date:  2010-11-16       Impact factor: 2.602

Review 2.  Review of numerical methods for simulation of mechanical heart valves and the potential for blood clotting.

Authors:  Mohamad Shukri Zakaria; Farzad Ismail; Masaaki Tamagawa; Ahmad Fazli Abdul Aziz; Surjatin Wiriadidjaja; Adi Azrif Basri; Kamarul Arifin Ahmad
Journal:  Med Biol Eng Comput       Date:  2017-07-26       Impact factor: 2.602

3.  Modified control grid interpolation for the volumetric reconstruction of fluid flows.

Authors:  David H Frakes; Kerem Pekkan; Lakshmi P Dasi; Hiroumi D Kitajima; Diane de Zelicourt; Hwa Liang Leo; Josie Carberry; Kartik Sundareswaran; Helene Simon; Ajit P Yoganathan
Journal:  Exp Fluids       Date:  2008-12       Impact factor: 2.480

4.  Device Thrombogenicity Emulator (DTE)--design optimization methodology for cardiovascular devices: a study in two bileaflet MHV designs.

Authors:  Michalis Xenos; Gaurav Girdhar; Yared Alemu; Jolyon Jesty; Marvin Slepian; Shmuel Einav; Danny Bluestein
Journal:  J Biomech       Date:  2010-05-21       Impact factor: 2.712

5.  Blood damage through a bileaflet mechanical heart valve: a quantitative computational study using a multiscale suspension flow solver.

Authors:  B Min Yun; Cyrus K Aidun; Ajit P Yoganathan
Journal:  J Biomech Eng       Date:  2014-10       Impact factor: 2.097

Review 6.  Computational Fluid Dynamics Assessment Associated with Transcatheter Heart Valve Prostheses: A Position Paper of the ISO Working Group.

Authors:  Zhenglun Alan Wei; Simon Johannes Sonntag; Milan Toma; Shelly Singh-Gryzbon; Wei Sun
Journal:  Cardiovasc Eng Technol       Date:  2018-04-19       Impact factor: 2.495

7.  Role of Computational Simulations in Heart Valve Dynamics and Design of Valvular Prostheses.

Authors:  Krishnan B Chandran
Journal:  Cardiovasc Eng Technol       Date:  2010-03       Impact factor: 2.495

8.  Mathematical modeling of flow-generated forces in an in vitro system of cardiac valve development.

Authors:  Stefanie V Biechler; Jay D Potts; Michael J Yost; Lorain Junor; Richard L Goodwin; John W Weidner
Journal:  Ann Biomed Eng       Date:  2009-10-28       Impact factor: 3.934

9.  A Three-Dimensional Computational Fluid Dynamics Model of Regurgitant Mitral Valve Flow: Validation Against in vitro Standards and 3D Color Doppler Methods.

Authors:  Annalisa Quaini; Suncica Canic; Giovanna Guidoboni; Roland Glowinski; Stephen R Igo; Craig J Hartley; William A Zoghbi; Stephen H Little
Journal:  Cardiovasc Eng Technol       Date:  2011-02-08       Impact factor: 2.495

10.  Altered shear stress stimulates upregulation of endothelial VCAM-1 and ICAM-1 in a BMP-4- and TGF-beta1-dependent pathway.

Authors:  Philippe Sucosky; Kartik Balachandran; Adnan Elhammali; Hanjoong Jo; Ajit P Yoganathan
Journal:  Arterioscler Thromb Vasc Biol       Date:  2008-11-20       Impact factor: 8.311

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